Table 2. Distribution of autoimmune regulator (AIRE) gene rs878081 alleles and genotypes in rheumatoid arthritis patients and healthy controls.

AIRE gene polymorphism	Patients (n = 298) (n, %)	Control (n = 299) (n, %)	OR (95%CI)	P value
Allele
C	421 (70.6%)	450 (75.3%)	Reference
T	175 (29.4%)	148 (24.7%)	1.26; (0.98-1.63)	0.073
Genotype
CC	156 (52.3%)	170 (56.9%)	Reference
CT	109 (36.6%)	110 (36.8%)	1.08; (0.77-1.52)	0.660
TT	33 (11.1%)	19 (6.3%)	1.89; (1.03-3.47)	0.039
CC+CT vs TT	265 / 33 (88.9 / 11.1)	280 / 19 (93.6 / 6.4)	1.84; (1.02-3.31)	0.043
TT+CT vs CC	142 / 156 (47.7 / 52.3)	129 / 170 (43.1 / 56.9)	1.19; (0.86-1.66)	0.269
HWE		0.831

HWE: Hardy Weinberg equation.