Table 5. Comparison of studied data according to autoimmune regulator (AIRE) genotypes in all rheumatoid arthritis (RA) cases.
| RA (n = 300) | P | ||
|---|---|---|---|
| CC + CT (n = 265) | TT (n = 33) | ||
| Age (years, mean±SD) | 54.66±15.73 | 53.45±13.42 | 0.673 |
| Males (n, %) | 124 (46.8%) | 10 (30.3%) | 0.073 |
| Females (n, %) | 141 (53.2%) | 23 (69.7%) | |
| Family history (n, %) | 71 (26.8%) | 5 (15.2%) | 0.148 |
| Onset (years, median±SD) | 45.65±12.86 | 43.91±10.16 | 0.455 |
| Morning stiffness (n, %) | 0.338 | ||
| 0 | 53 (20.0%) | 7 (21.2%) | |
| <1 hour | 152 (57.4%) | 15 (45.5%) | |
| >1 hour | 60 (22.6%) | 11 (33.3%) | |
| Deformities (n, %) | 103 (38.9%) | 9 (27.3%) | 0.195 |
| ESR (median±SD) | 33.55±21.73 | 36.82±23.20 | 0.419 |
| Positive CRP (n, %) | 161 (60.8%) | 22 (66.7%) | 0.511 |
| Positive RF (n, %) | 213 (80.4%) | 27 (81.8%) | 0.844 |
| Tender joints (median±SD) | 8.51±5.84 | 10.06±5.83 | 0.150 |
| Swollen joints (median±SD) | 10.32±5.59 | 9.58±5.15 | 0.465 |
| DAS (median±SD) | 4.36±1.62 | 4.32±1.53 | 0.905 |
ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; RF: rheumatoid factor; DAS: disease activity score in 28 joints. Statistical analyses were carried out with the t-test and chi-squared test.