Figure 4.

Efficiency metrics (M Criterion, Observed Fuzziness and Class-Averaged Observed Fuzziness) for Dataset1, Dataset2, and Dataset3. (A) Dataset2 without extending with assumed non-actives. Circles show individual results from the three replicate runs that were run, while the lines show the median value from the individual replicate results. Targets are here sorted by number of active compounds. (B) Dataset2 after extending with assumed non-actives. Circles show individual results from the three replicate runs that were run, while the lines show the median value from the individual replicate results. Targets are here sorted by number of active compounds. (C) Dataset3, the 10 largest target datasets, which were not extended with assumed non-actives. Targets are here sorted by total number of compounds.