Table 4.

Association between comorbidities and all-cause mortality. Results of Cox proportional hazard model with comorbidities as time-dependent covariate (N = 972)

Comorbidity	HR (95% CI)a	P-Value	HR (95% CI)b	P-Value
Bronchiectasis	0.84 (0.44; 1.62)	0.612	0.83 (0.40; 1.86)	0.633
Splenomegaly	2.11 (1.17; 3.82)	0.013	1.67 (0.82; 3.39)	0.155
Autoimmunity (organ/ systemic)	1.61 (0.79; 3.27)	0.187	1.52 (0.67; 3.43)	0.311
Autoimmune cytopenia	0.72 (0.22; 2.35)	0.591	1.08 (0.33; 3.57)	0.897
Enteropathy	1.39 (0.54; 3.56)	0.493	0.97 (0.28; 3.41)	0.962
Solid tumor	3.19 (1.55; 6.57)	0.002	2.69 (1.10; 6.57)	0.030
Lymphoma	3.95 (1.81; 8.66)	0.001	5.48 (2.36; 12.71)	<.0001
GLILD	3.80 (1.47; 9.85)	0.006	4.85 (1.63; 14.39)	0.005

^aunivariable analysis

^badjusted for age of CVID symptoms onset