Table 5.
Results of an explorative survival risk factor analysis. Results are obtained with Cox proportional hazards model (N = 2700)
| Risk factor | HR: Mean (95% CI) | P value |
|---|---|---|
| Age at diagnosisa | 1.04 (1.03; 1.05) | <.0001 |
| Age at symptoms onseta | 1.04 (1.03, 1.05) | <.0001 |
| Sex (female)a | 1.14 (0.77; 1.69) | 0.515 |
| Age at diagnosisb | 1.05 (1.04–1.06) | <.0001 |
| Age at symptoms onsetb | 1.05 (1.04–1.06) | <.0001 |
| Consanguinityc | 4.42 (1.66; 11.75) | 0.003 |
| Monthly Ig dosec | 1.00 (0.99; 1.00) | 0.780 |
| Diagnostic delayd | 0.99 (0.97–1.01) | 0.221 |
| Diagnostic delaye | 1.04 (1.02; 1.06) | 0.0003 |
aresuls of a univariable analysis
bresults adjusted for diagnostic delay
cresults stratified for the age at CVID diagnosis and sex
dresults adjusted for the age at CVID diagnosis
eresults adjusted for the age of symptoms onset