Table 2. Echocardiographic Parameters in 150 Patients With Asymptomatic Severe Aortic Stenosis at Baseline vs Follow-up Divided by Symptom Status at Follow-up Echocardiography.
| Variable | Symptomatic at Follow-up (n = 78) | Asymptomatic at Follow-up (n = 72) | P Value Intergroup | |||||
|---|---|---|---|---|---|---|---|---|
| Mean (SD) | P Value | Mean (SD) | P Value | Baseline | Follow-up | |||
| Baseline | Follow-up | Baseline | Follow-up | |||||
| Aortic valve | ||||||||
| Mean gradient, mm Hg | 38.4 (11.6) | 49.0 (15.8) | <.001 | 39.4 (13.5) | 46.6 (15.8) | <.001 | .71 | .31 |
| Peak velocity, m/s | 3.9 (0.6) | 4.4 (0.6) | <.001 | 4.0 (0.6) | 4.3 (0.6) | <.001 | .36 | .25 |
| Area, cm2 | 0.88 (0.1) | 0.76 (0.1) | <.001 | 0.85 (0.1) | 0.79 (0.1) | .05 | .12 | .30 |
| Area index, cm2/m2 | 0.48 (0.1) | 0.41 (0.1) | <.001 | 0.46 (0.1) | 0.42 (0.1) | .02 | .08 | .41 |
| Stroke volume, mL | 81.1 (14.6) | 80.6 (14.8) | .17 | 81.7 (19.5) | 82.1 (19.2) | .71 | .97 | .91 |
| Stroke volume index, mL/m2 | 44.6 (9.0) | 43.7 (8.5) | .34 | 43.6 (10.1) | 43.5 (8.3) | .94 | .55 | .84 |
| LV | ||||||||
| Mass index, g/m2 | 114.0 (27.1) | 129.6 (29.2) | <.001 | 113.7 (30.6) | 121.0 (29.6) | .01 | .76 | .06 |
| Ejection fraction, % | 61.4 (6.3) | 61.6 (6.9) | .25 | 61.0 (5.0) | 59.5 (8.2) | .28 | .65 | .06 |
| Global longitudinal strain, % | −17.7 (2.6) | −16.3 (2.9) | <.001 | −18.2 (2.6) | −16.4 (2.6) | <.001 | .21 | .83 |
Abbreviations: AVR, aortic valve replacement; LV, left ventricular.