Table 1. Characteristics of Major Congenital Heart Disease in Denmark.
| CHD | Prenatal Diagnosis, No./Total No. (%) | P Value | P Valuea | Associated Anomalies, No./Total No. (%) | ||
|---|---|---|---|---|---|---|
| No General Screening | General Screening | Chromosomal Anomaly | Noncardiovascular Malformation | |||
| UVH | 108/315 (34.3) | 269/323 (83.3) | <.001 | <.001 | 35/638 (5.5) | 141/638 (22.1) |
| ccTGA | 4/26 (15) | 16/25 (64) | <.001 | .005 | 1/51 (2) | 9/51 (18) |
| Truncus arteriosus | 8/37 (21) | 12/24 (50) | .02 | .27 | 12/61 (20) | 19/61 (31) |
| TGA | 7/163 (4.3) | 63/171 (36.8) | <.001 | <.001 | 4/334 (1.2) | 60/334 (18.0) |
| IAA | 1/26 (4) | 12/31 (39) | .002 | .02 | 17/57 (30) | 20/57 (35) |
| AVSD | 47/281 (16.7) | 91/180 (50.6) | <.001 | <.001 | 240/461 (52.1) | 153/461 (33.2) |
| DORV | 10/75 (13) | 31/64 (48) | <.001 | <.001 | 17/139 (12.2) | 46/139 (33.1) |
| CoA | 9/255 (3.5) | 29/235 (12.3) | <.001 | .004 | 40/490 (8.2) | 104/490 (21.2) |
| Ebstein anomaly | 5/28 (18) | 12/25 (48) | .02 | .25 | 3/53 (6) | 4/53 (8) |
| PA-VSD | 4/52 (8) | 11/34 (32) | .003 | .04 | 19/86 (22) | 43/86 (50) |
| PA-IVS | 4/23 (17) | 7/12 (58) | .02 | .29 | 1/35 (3) | 6/35 (17) |
| TOF | 7/147 (4.8) | 48/143 (33.6) | <.001 | <.001 | 39/290 (13.4) | 83/290 (28.6) |
| Total | 214/1428 (15.0) | 601/1267 (47.4) | <.001 | <.001 | 428/2695 (15.9) | 688/2695 (25.5) |
Abbreviations: AVSD, atrioventricular septal defects; ccTGA, congenitally corrected transposition of the great arteries; CoA, coarctation of the aorta; DORV, double outlet right ventricle; IAA, interrupted aortic arch; PA-IVS, pulmonary atresia with intact ventricle septum; PA-VSD, pulmonary atresia with ventricular septal defect; TGA, transposition of the great arteries; TOF, tetralogy of Fallot; UVH, univentricular hearts.
a
Adjusted for multiple testing with Bonferroni Correction.