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. 2018 Jul 18;3(9):829–837. doi: 10.1001/jamacardio.2018.2009

Table 2. Termination of Pregnancy in Major Congenital Heart Disease in Denmark.

CHD Total, No./Total No. (%) P Valuea Prenatally Diagnosed, No./Total No. (%) P Valuea
No General Screening General Screening P Value No General Screening General Screening P Value
UVH 70/315 (22.2) 216/323 (66.9) <.001 <.001 70/108 (64.8) 216/269 (80.3) .002 .03
ccTGA 0/26 6/25 (24) .01 .13 0/4 6/16 (38) .27 >.99
Truncus arteriosus 7/37 (19) 11/24 (67) .02 .32 7/8 (88) 11/12 (2) >.99 >.99
TGA 5/163 (3.1) 11/171 (10.1) .15 >.99 5/7 (71) 11/63 (18) .006 .07
IAA 0/26 6/31 (19) .03 .35 0/1 6/12 (50) >.99 >.99
AVSD 33/281 (11.7) 60/180 (33.3) <.001 <.001 33/47 (70) 60/91 (66) .61 >.99
DORV 2/75 (3) 18/64 (28) <.001 <.001 2/10 (20) 18/31 (58) .07 .87
CoA 1/255 (0.4) 2/235 (0.9) .61 >.99 1/9 (11) 2/29 (7) >.99 >.99
Ebstein anomaly 2/28 (7) 2/25 (8) >.99 >.99 2/5 (40) 2/12 (17) .54 >.99
PA-VSD 1/52 (2) 4/34 (12) .08 >.99 1/4 (25) 4/11 (36) >.99 >.99
PA-IVS 2/23 (9) 1/12 (8) >.99 >.99 2/4 (50) 1/7 (14) .49 >.99
TOF 1/147 (0.7) 10/143 (7.0) .005 .06 1/7 (14) 10/48 (21) >.99 >.99
Total 124/1428 (8.7) 347/1267 (27.4) <.001 <.001 124/214 (57.9) 347/601 (57.7) .96 >.99

Abbreviations: AVSD, atrioventricular septal defects; ccTGA, congenitally corrected transposition of the great arteries; CHD, congenital heart disease; CoA, coarctation of the aorta; DORV, double outlet right ventricle; IAA, interrupted aortic arch; PA-IVS, pulmonary atresia with intact ventricle septum; PA-VSD, pulmonary atresia with ventricular septal defect; TGA, transposition of the great arteries; TOF, tetralogy of Fallot; UVH, univentricular hearts.

a

Adjusted for multiple testing with Bonferroni Correction.