Table 2. Termination of Pregnancy in Major Congenital Heart Disease in Denmark.
CHD | Total, No./Total No. (%) | P Valuea | Prenatally Diagnosed, No./Total No. (%) | P Valuea | ||||
---|---|---|---|---|---|---|---|---|
No General Screening | General Screening | P Value | No General Screening | General Screening | P Value | |||
UVH | 70/315 (22.2) | 216/323 (66.9) | <.001 | <.001 | 70/108 (64.8) | 216/269 (80.3) | .002 | .03 |
ccTGA | 0/26 | 6/25 (24) | .01 | .13 | 0/4 | 6/16 (38) | .27 | >.99 |
Truncus arteriosus | 7/37 (19) | 11/24 (67) | .02 | .32 | 7/8 (88) | 11/12 (2) | >.99 | >.99 |
TGA | 5/163 (3.1) | 11/171 (10.1) | .15 | >.99 | 5/7 (71) | 11/63 (18) | .006 | .07 |
IAA | 0/26 | 6/31 (19) | .03 | .35 | 0/1 | 6/12 (50) | >.99 | >.99 |
AVSD | 33/281 (11.7) | 60/180 (33.3) | <.001 | <.001 | 33/47 (70) | 60/91 (66) | .61 | >.99 |
DORV | 2/75 (3) | 18/64 (28) | <.001 | <.001 | 2/10 (20) | 18/31 (58) | .07 | .87 |
CoA | 1/255 (0.4) | 2/235 (0.9) | .61 | >.99 | 1/9 (11) | 2/29 (7) | >.99 | >.99 |
Ebstein anomaly | 2/28 (7) | 2/25 (8) | >.99 | >.99 | 2/5 (40) | 2/12 (17) | .54 | >.99 |
PA-VSD | 1/52 (2) | 4/34 (12) | .08 | >.99 | 1/4 (25) | 4/11 (36) | >.99 | >.99 |
PA-IVS | 2/23 (9) | 1/12 (8) | >.99 | >.99 | 2/4 (50) | 1/7 (14) | .49 | >.99 |
TOF | 1/147 (0.7) | 10/143 (7.0) | .005 | .06 | 1/7 (14) | 10/48 (21) | >.99 | >.99 |
Total | 124/1428 (8.7) | 347/1267 (27.4) | <.001 | <.001 | 124/214 (57.9) | 347/601 (57.7) | .96 | >.99 |
Abbreviations: AVSD, atrioventricular septal defects; ccTGA, congenitally corrected transposition of the great arteries; CHD, congenital heart disease; CoA, coarctation of the aorta; DORV, double outlet right ventricle; IAA, interrupted aortic arch; PA-IVS, pulmonary atresia with intact ventricle septum; PA-VSD, pulmonary atresia with ventricular septal defect; TGA, transposition of the great arteries; TOF, tetralogy of Fallot; UVH, univentricular hearts.
Adjusted for multiple testing with Bonferroni Correction.