Table 1.
Characteristics of normal and RAS pigs with or without MetS (n = 7 each)
| Normal | RAS | MetS-RAS | |
|---|---|---|---|
| Body weight (kg) | 52.3 ± 0.7 | 50.2 ± 2.5 | 92.4 ± 2.3* |
| Degree of stenosis (%) | – | 64.8 ± 3.8 | 65.0 ± 5.0 |
| MAP (mm Hg) | 89.6 ± 2.1 | 97.2 ± 2.0* | 129.6 ± 9.1*† |
| Creatinine (mg/dl) | 1.2 ± 0.1 | 1.6 ± 0.1* | 1.7 ± 0.1* |
| Total cholesterol (mg/dl) | 71 (67.5–84) | 91 (79.2–106.5) | 506 (365.2–723.2)*† |
| Triglyceride (mg/dl) | 7.0 ± 0.3 | 11.9 ± 0.9 | 15.1 ± 3.0* |
| LDL cholesterol (mg/dl) | 26.6 (22–31.7) | 39.2 (34–44.4) | 444 (277.4–555.2)*† |
| Urine ACR (mg/g) | 9.9 (4.4–20.6) | 16.2 (13.3–536.4) | 12.0 (5.4–79.9) |
Data are mean ± SEM or median (interquartile range). Abbreviations: ACR, albumin to creatinine ratio; LDL, low-density lipoprotein; MAP, mean arterial pressure; MetS, metabolic syndrome; RAS, renal artery stenosis.
*P < 0.05 vs. normal.
† P < 0.05 vs. RAS.