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. Author manuscript; available in PMC: 2019 Sep 21.
Published in final edited form as: ACS Chem Biol. 2018 Sep 12;13(9):2699–2707. doi: 10.1021/acschembio.8b00645

Table 4.

CurK DH Activity

Percent distribution of substrate & products (cmpd)
Starting material 3-hydroxy 2-enoyl 3-enoyl
Wild type
9 49.1 ± 0.2 (9) 50.9 ± 0.2 (10) < 0.01 (11)
10 & 11 (2:1) 34.8 ± 0.3 (9) 34.9 ± 0.1 (10) 30.3 ± 0.3 (11)
P1005V
9 60.2 ± 0.3 (9) 38.4 ± 0.2 (10) 1.4 ± 0.2 (11)
10 & 11 (2:1) 34.9 ± 0.3 (9) 36.9 ± 0.5 (10) 28.2 ± 0.7 (11)