Table 3:
Heart failure computable phenotype algorithms deployed within the Learning Health Systems‡ PCORnet Clinical Data Research Network, Query period 2013–2016.
| Algorithm | Age Group | Heart failure population identified |
Total Population |
||
|---|---|---|---|---|---|
| N | % | ||||
| ≥1 HF code* (Table 1, Algorithm 1) | 30–49 | 26,903 | 0.79% | 3,423,297 | |
| 50–64 | 61,532 | 2.4% | 2,493,470 | ||
| 65+ | 166,117 | 9.0% | 1,838,350 | ||
| All | 254,552 | 3.28% | 7,755,117 | ||
| ≥2 HF codes (Table 1, Algorithm 4) | 30–49 | 13,686 | 0.40% | 3,423,297 | |
| 50–64 | 31,471 | 1.26% | 2,493,470 | ||
| 65+ | 88,858 | 4.83% | 1,838,350 | ||
| All | 134,015 | 1.73% | 7,755,117 | ||
| ≥2 HF codes + any HF medicationf† (Table 1. Algorithm 5) |
30–49 | 6,797 | 0.23% | 2,954,319 | |
| 50–64 | 18,951 | 0.88% | 2,143,829 | ||
| 65+ | 49,028 | 3.08% | 1,592,416 | ||
| All | 74,776 | 1.12% | 6,690,564 | ||
Heart failure code is International Classification of Diseases – 9th Revision, Clinical Modification code 428.
Heart failure medications include aldosterone antagonists (eplerenone, spironolactone), HF specific beta blockers (bisoprolol, carvedilol, metoprolol succinate), loop diuretics (bumetanide, ethacrynic acid, furosemide, torsemide), digoxin, angiotensin converting enzyme inhibitors and angiotensin receptor blockers.
These algorithms were deployed within the Learning Health Systems (LHSnet) Clinical Data Research Network of PCORnet. LHSnet is comprised of 6 health systems (Mayo Clinic, Allina Health System, Essentia Health, Intermountain Health Care, University of Michigan and Ohio State University); 1 health plan (Medica Research Institute); 1 data partner based in a university (Arizona State University); and 1 local public health department (Olmsted County Public Health Services). Two health systems did not have medication data available and were not included in queries requiring medication data.