Table 2. Univariate Analysis of the Risk for BP Under DPP-4 Inhibitor Exposure, Stratified by Sex and Age.
| Subgroup | No. | DPP-4 Inhibitor Exposure, No. (%) | OR (95% CI) | P Value | |
|---|---|---|---|---|---|
| Patients With BP (n = 82) |
Controls (n = 328) |
||||
| All | 410 | 36 (43.9) | 71 (21.6) | 2.83 (1.70-4.71) | <.001 |
| Age, y | |||||
| 0-69 | 71 | 10 (58.8) | 11 (20.4) | 5.58 (1.73-18.01) | .002 |
| 70-79 | 111 | 10 (58.8) | 29 (30.9) | 3.20 (1.11-9.25) | .03 |
| ≥80 | 228 | 16 (33.3) | 31 (17.2) | 2.40 (1.18-4.91) | .01 |
| Sex | |||||
| Male | 190 | 21 (55.3) | 33 (21.7) | 4.46 (2.11-9.40) | <.001 |
| Female | 220 | 15 (34.1) | 38 (21.6) | 1.88 (0.92-3.86) | .08 |
Abbreviations: BP, bullous pemphigoid; DPP-4 inhibitor, dipeptidyl peptidase 4 inhibitor; OR odds ratio.