Table. Calculated Mutation Rate for Uveal Melanomas With Different Thicknesses Based on the 5-Year Metastasis Rate Published by Shields et al6.
Thickness, mm | Cells in Tumor Mass, No. | 5-y Metastasis Rate, % | Mutation Rate |
---|---|---|---|
0-1.0 | 7.25 × 106 | 5.70 | 7.86 × 10−7 |
1.1-2.0 | 6.07 × 107 | 7.90 | 1.30 × 10−7 |
2.1-3.0 | 1.56 × 108 | 4.60 | 2.94 × 10−8 |
3.1-4.0 | 2.82 × 108 | 8.10 | 2.87 × 10−8 |
4.1-5.0 | 4.25 × 108 | 15.20 | 3.57 × 10−8 |
5.1-6.0 | 5.75 × 108 | 17.30 | 3.01 × 10−8 |
6.1-7.0 | 9.72 × 108 | 15.20 | 1.56 × 10−8 |
7.1-8.0 | 1.18 × 109 | 21.30 | 1.80 × 10−8 |
8.1-9.0 | 1.37 × 109 | 31.10 | 2.27 × 10−8 |
9.1-10.0 | 2.62 × 109 | 30.70 | 1.17 × 10−8 |
>10.0 | 3.46 × 109 | 40.20 | 1.16 × 10−8 |