Figure 4. Randomized Clinical Trials of Levothyroxine Therapy in Subclinical Hypothyroidism Outcomes on Body Mass Index.

Weights are derived from a random-effects meta-analysis of differences in body mass index (calculated as weight in kilograms divided by height in meters squared). Sizes of data markers indicate weight of studies. Dashed vertical line represents overall mean effect. Numbers differ between participants randomized and participants with available outcome data in the studies by Kong et al,²⁷ Teixeira et al,³⁰ and Stott et al¹² (see Table and eTable 2 in Supplement 1). The study by Razvi et al³² is a crossover study that included 100 participants.