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. 2018 Oct 2;320(13):1338–1348. doi: 10.1001/jama.2018.13467

Table 3. Association of Risk Factors With Hypertension Among Men.

Potential Mediating Factor Sample Size Age-Adjusted Least-Squares Mean (95% CI)a Age-Adjusted Difference Between White and Black Participants (95% CI) Adjusted Odds Ratio (95% CI)b Adjusted Incidence Proportion (95% CI) Absolute Risk Difference in Incidence (95% CI)
White Black White Men Black Men Factor Absent or 25th Percentile of Factor Factor Present or 75th Percentile of Factor
Education level ≤high school 2430 695 0.20 (0.18 to 0.22) 0.38 (0.35 to 0.42) −0.18 (−0.22 to −0.15) 1.22 (1.02 to 1.47)c 34.0 (32.0 to 35.9) 38.7 (34.6 to 42.4) 4.6 (0.1 to 8.8)
Income ≤$35 000 2234 637 0.23 (0.21 to 0.25) 0.42 (0.39 to 0.46) −0.19 (−0.23 to −0.15) 1.20 (1.00 to 1.45)c 34.3 (32.2 to 36.4) 38.6 (34.7 to 42.6) 4.3 (0 to 8.9)
Body mass indexd 2426 693 27.3 (27.1 to 27.6) 27.6 (27.2 to 27.9) −0.3 (−0.7 to 0.1) 1.22 (1.13 to 1.32)e 32.1 (30.5 to 35.0) 37.3 (35.8 to 40.3) 5.2 (3.2 to 7.7)
Waist circumference, cm 2427 694 96.8 (96.3 to 97.4) 95.7 (94.8 to 96.6) 1.2 (0.1 to 2.2) 1.18 (1.09 to 1.27)e 32.5 (30.5 to 34.6) 36.9 (34.9 to 39.2) 4.4 (2.3 to 9.2)
Heavy alcohol usef 2398 677 0.04 (0.03 to 0.05) 0.03 (0.02 to 0.05) 0.01 (−0.01 to 0.03) 0.97 (0.67 to 1.40)c 34.8 (33.0 to 36.8) 34.1 (26.4 to 42.7) −0.8 (−8.6 to 7.9)
Does not exercise 2405 687 0.20 (0.18 to 0.22) 0.24 (0.21 to 0.28) −0.04 (−0.08 to 0) 0.98 (0.81 to 1.18)c 35.0 (32.9 to 36.9) 34.5 (30.8 to 38.1) −0.5 (−4.5 to 3.7)
Depression scale score (CESD-4)g 2410 689 0.57 (0.51 to 0.64) 0.91 (0.80 to 1.03) −0.34 (−0.47 to −0.21) 1.05 (0.97 to 1.13)e 34.6 (32.2 to 36.5) 34.3 (33.2 to 37.1) 0.7 (−0.4 to 1.9)
Perceived Stress Scale scoreh 2430 695 2.40 (2.28 to 2.51) 2.86 (2.66 to 3.05) −0.46 (−0.69 to −0.23) 1.00 (0.92 to 1.08)e 35.2 (32.5 to 37.6) 35.0 (32.9 to 37.0) −0.2 (−2.8 to 2.5)
DASH diet scorei 2067 422 13.3 (13.1 to 13.6) 14.7 (14.3 to 15.1) −1.4 (−1.8 to −0.9) 1.05 (0.96 to 1.15)e 33.5 (30.9 to 36.3) 35.3 (35.3 to 37.8) 1.8 (−1.2 to 4.6)
Mediterranean diet scorej 2043 411 4.47 (4.38 to 4.56) 4.19 (4.02 to 4.36) 0.28 (0.09 to 0.48) 1.01 (0.92 to 1.10)e 34.1 (31.7 to 36.7) 34.3 (34.3 to 37.0) 0.2 (−3.1 to 3.3)
Southern diet scorek 2067 422 −0.26 (−0.31 to −0.21) 0.81 (0.72 to 0.90) −1.07 (−1.17 to −0.97) 1.16 (1.06 to 1.27)e 32.4 (29.9 to 34.9) 36.1 (33.8 to 38.3) 3.7 (1.4 to 6.2)
Ratio of sodium to potassiuml 2067 422 0.89 (0.87 to 0.98) 0.98 (0.95 to 1.00) −0.09 (−0.12 to −0.06) 1.11 (1.01 to 1.20)e 32.9 (30.4 to 35.5) 35.8 (33.5 to 38.2) 2.9 (0.4 to 5.5)

Abbreviations: CESD-4, 4-item Center for Epidemiologic Studies Depression Scale; DASH, Dietary Approaches to Stop Hypertension.

a

For dichotomous variables, the data have been scored 0 for “no” and 1 for “yes”; therefore, the mean is equivalent to the proportion.

b

Adjusted for age, race, and baseline systolic blood pressure for the risk factor of incident hypertension. For example, data on education were available on 2430 white participants and 695 black participants. The age-adjusted estimate of the proportion with an education level ≤high school was 20% for white participants (95% CI, 18% to 22%) and 38% for black participants (95% CI, 35% to 42%), which differed by 18% (95% CI, 15% to 22%). The odds of developing hypertension during follow-up was 1.22-times higher for those with an education level ≤high school (relative to those with >high school education level); 38.7% (95% CI, 34.6% to 42.4%) of those with an education level ≤high school developed hypertension vs 34.0% (95% CI, 32.0% to 35.9%) of those with >high school education level developed hypertension, which differed by 4.6% (95% CI, 0.1% to 8.8%).

c

Expressed as the difference in a dichotomous predictor.

d

Calculated as weight in kilograms divided by height in meters squared.

e

Expressed for a 1-SD difference in a continuous predictor.

f

Defined according to the National Institute on Alcohol Abuse and Alcoholism as ≥7 drinks per week in women or ≥14 drinks per week in men.

g

Range from 0 to 12; higher scores represent more depressive symptoms.

h

Range from 0 to 16; higher scores present more perceived stress.

i

Original score subtracted from 38; range from 0 to 29; higher scores reflect being less compliant with the diet.

j

Original score subtracted from 9; range from 0 to 9; higher scores reflect being less compliant with the diet.

k

Range from −4.5 to 8.2; higher scores reflect being more compliant with the diet.

l

Range from 0.3 to 2.5; higher scores represent a greater intake of sodium relative to potassium.