Skip to main content
. 2018 Oct 29;14(10):e1007738. doi: 10.1371/journal.pgen.1007738

Fig 6. Reduced Twist1 limb expression and polydactyly in eTw5-7Δ\Δ.

Fig 6

(A) Hindlimb autopods and corresponding skeletal preparations of wild type (WT) and eTw5-7Δ\Δ mice. Pre-axial polydactyly is presented in eTw5-7Δ\Δ mice. (B) Top: mouse whole mount in situ hybridization of Twist1 in WT and eTw5-7Δ\Δ mice at E11.5. Bottom: Reduced Twist1 expression in E11.5 limb bud along the anterior-posterior axes in eTw5-7Δ\Δ. (C) Expression levels of Twist1 and Hdac9 in the mouse E11.5 hindlimb of wild type and eTw5-7Δ\Δ mice measured by quantitative RT-PCR (p>0.05, Student’s t-test).