Table 5.

Effects of Exercise on Systemic and Adipose Tissue Inflammation

	EX group N=10	CON group N=10	p-valuea	Effect Sizeb
CRP, mg/dL
PRE	3.20 ± 0.64	4.01 ± 0.25	0.005
CHANGE	−0.92 ± 0.72	0.40 ± 0.84	0.0008	1.29
Within group p-valuec	0.008	0.50
Leptin, ng/mL
PRE	12.2 ± 2.0	12.5 ± 2.0	0.91
CHANGE	−3.0 ± 1.9	1.9 ± 1.6	0.0004	1.60
Within group p-valuec	0.008	0.016
Adiponectin, ng/mL
PRE	13.2 ± 1.7	13.0 ± 1.8	0.62
CHANGE	8.7 ± 2.1	−1.6 ± 2.8	0.0001	1.78
Within group p-valuec	0.002	0.13
IL-6, ng/dL
PRE	3.15 ± 0.49	3.23 ± 0.51	0.68
CHANGE	−1.02 ± 0.53	0.42 ± 0.35	0.0002	1.67
Within group p-valuec	0.002	0.004
IL-8, ng/dL
PRE	5.53 ± 1.00	5.46 ± 0.62	0.91
CHANGE	−1.28 ± 0.80	0.48 ± 0.56	0.0002	1.57
Within group p-valuec	0.002	0.016
M1, %
PRE	24.0 ± 6.2	26.3 ± 7.9	0.65
CHANGE	−17.4 ± 7.1	3.0 ± 4.8	0.0001	1.70
Within group p-valuec	0.002	0.13
M2, %
PRE	4.0 ± 1.3	4.3 ± 1.1	0.76
CHANGE	9.0 ± 1.6	−0.4 ± 1.0	0.0002	1.88
Within group p-valuec	0.002	0.31
Adiponectin, ng/mLd
PRE	91.68 ± 21.05	88.58 ± 37.81	0.65
CHANGE	46.61 ± 25.19	−13.83 ± 26.03	0.008	1.52
Within group p-valuec	0.03	0.31
IL-12 p40, pg/mLd
PRE	8.83 ± 13.13	11.48 ± 19.45	1.00
CHANGE	1.93 ± 20.18	50.36 ± 44.57	0.055	1.20
Within group p-valuec	0.75	0.13
IL-12 p70, pg/mLd
PRE	2.53 ± 1.06	1.70 ± 1.32	0.46
CHANGE	−1.02 ± 2.12	1.56 ± 1.62	0.08	1.14
Within group p-valuec	0.28	0.063

^aWilcoxon rank sum test

^bEffect size: difference between groups divided by SD

^cWilcoxon signed rank test

^dAdipose tissue cytokine secretions

Abbreviations: CRP, C-reactive protein; IL-6,8,12 Interleukin-6,8,12, TNF- α, tumor necrosis factor- α