Table 3.
Epithelial ESR1 is undetectable at 14 weeks, sparsely expressed at 16 weeks and predominant at 21 weeks. Xenografts of 13-week uterine corpus (before expression of ESR1) when treated with DES exhibit prominent uterine epithelial ESR1 immunoreactivity.
Epithelial PGR is induced in xenografts by DES. From (Cunha et al., 2017b).