Table 4.
Propensity Model-Adjusted Adverse Outcomes by Treatment
| Adverse Outcomes | Treatment | ||
|---|---|---|---|
| Radical Prostatectomy and Adjuvant Radiotherapy (N=451) % |
Radiotherapy and Androgen Deprivation Therapy (N=2590) % |
P-value | |
| Urinary Incontinence | |||
| Diagnosis | 49.1 | 19.4 | <.0001 |
| Procedures | 12.4 | 1.6 | 0.0007 |
| Erectile Dysfunction | |||
| Diagnosis | 28.3 | 20.4 | 0.0212 |
| Procedures | 8.4 | 3.7 | 0.0186 |
| Other Genitourinary | |||
| Radiation cystitis | 8.6 | 6.0 | 0.1635 |
| Hematuria | 40.7 | 34.0 | 0.0963 |
| Bladder neck contracture/ Urethral stricture |
|||
| Diagnosis | 37.6 | 18.3 | <.0001 |
| Procedure | 34.3 | 12.8 | <.0001 |
| Urinary fistula | 2.9 | 1.8 | 0.2872 |
| Gastrointestinal | |||
| Radiation proctitis | 5.6 | 7.7 | 0.2345 |
| Diarrhea | 24.7 | 23.5 | 0.7229 |
| Rectal bleeding | 47.1 | 46.9 | 0.9575 |
| Cardiac | |||
| Acute myocardial infarction | 19.2 | 18.3 | 0.7648 |
| Ventricular arrhythmias | 18.7 | 12.1 | 0.0152 |
| Coronary artery disease | 55.4 | 44.0 | 0.0083 |
| Pulmonary | |||
| Pulmonary embolus | 7.2 | 8.8 | 0.4455 |
| Vascular | |||
| Venous embolism/thrombosis | 25.4 | 24.0 | 0.6714 |
| Transient cerebral ischemia/stroke |
47.1 | 42.0 | 0.1997 |
| Peripheral arterial disease | 39.8 | 37.4 | 0.5227 |
| Endocrine | |||
| Diabetes Mellitus | 42.4 | 32.5 | 0.0157 |
| Musculoskeletal | |||
| Fracture | 33.6 | 30.7 | 0.4003 |
| Osteoporosis | 18.9 | 19.8 | 0.8027 |