Table 5.

Epithelial differentiation markers during human prostatic development

	Pre-bud	Newly emerged solid buds	Bud elongation and branching		Canalized ducts (12–19wks)
			Canalized	Solid	Basal cells	Luminal cells	Urethra
Markers
K6	+	+	+	+ & -	+	-	+
K7	+	+	+	- & -	-	+	+
				/+
K8	+	+	+	- &−/+	-	+	+
K10	-	-	-	-	-	-	-
K14	-	-	-	-	- & −/+	-	-
K15	-	+	+	+	+	-	+
K19	+	+	+	+	-	+	+
Runxl	?	+	+	+	- & −/+	+	+
P63	+	+	+	+	+	-	+
Foxa1	+	+	+	+	+	+	+
Pax2	-	-	-	-	-	-	-
Uroplakin	-	-	-	-	-	- & −/+	+
AR	+	+	+	+/−	- & −/+	+	+