Table 6.

Epithelial immunohistochemical profile of xenografts of human fetal prostates and human female urethras.

Markers*	Prostatic xenografts (DHT)	Female urethral xenografts (DHT)	Prostatic xenografts (control)	Female urethral xenografts (control)
Morphology	Canalized ducts	Canalized ducts	Solid “ducts”	Solid “ducts”
Keratin 7	Luminal cells only	Luminal cells only	Central cells**	Central cells**
Keratin 8	Luminal cells only	Luminal cells only	Central cells**	Central cells**
Keratin 14	Negative	Negative	Negative	Negative
Keratin 19	All epithelial cells	All epithelial cells	All epithelial cells	All epithelial cells
TP63	Basal cells only	Basal cells only	Basal & central cells	Basal & central cells
Androgen receptor	Luminal cells only	Luminal cells only	Negative	Negative
FOXA1	Positive	Positive	Positive	Positive
NKX3.1	Positive	Positive	Positive	Negative
PSA	ND	Positive	ND	Negative
PAP	ND	Positive	ND	Negative

^*Only the predominant phenotype is reported. For additional information, see text.

^**Central cells located in the core of solid ducts.

PSA=prostate specific antigen; PAP=prostatic acid phosphatase ND=not done