Fig. 3. AHR signaling does not drive anti-inflammatory properties to T_H17 cells.

Quantitative RT-PCR analysis of Rorc, Tbx21, Maf, Il17a, Il22, Csf2, and l10 from WT (white bars) or Ahr-deficient (green bars) cells differentiated for 72 h under nonpathogenic (TGFβ1 and IL-6) and pathogenic T_H17 cell conditions (TGFβ1, IL-6 plus IL-23 or IL-1β, IL-6 and IL-23). b Frequency of IL-17A⁺, IL-10⁺, and GM-CSF⁺ cells from WT and Ahr^−/− naive CD4⁺ T cells differentiated for 72 h with TGFβ1+IL-6+IL-23 under FICZ stimulation. NS not significant; *P < 0.05 and ***P < 0.001 (two-way ANOVA)