Fig. 2. The pro-proliferative effect of xCT in human melanomas.

a Western immunoblots on protein lysates from several stable clones that have been transfected with either empty vector or exogenous xCT cDNA in two melanoma cell lines (SK-mel2 and SK-mel187) with the lowest endogenous xCT expression (Fig. 1a). b Cellular growth was measured on stable xCT or empty vector clones derived from SK-mel2 and SK-mel187 cells. Viable cells were counted using trypan blue exclusion method