Table 1. Clinical features, initial management and follow up of patients presenting with acute, non-traumatic adrenal haemorrhage.
No. | Age/gender | Clinical features and predisposing factors (other than abdominal pain) | Urgent intervention | Functionality | Follow up/status | Final diagnosis/pathology | Outcomes |
---|---|---|---|---|---|---|---|
1 | 77/M | Hypertension, on rivaroxaban | No | No | Repeat CT—reduced size with benign features; no surgery | Likely benign | Died of non-adrenal cause 28 months after presentation |
2 | 89/F | INR 4.5, on warfarin | No | No | Repeat CT—increased size with features of malignancy; no surgery | Likely malignant | Died of non-adrenal cause 12 months after presentation |
3 | 68/M | Hypertension, excessive sweating and feeling unwell, on rivaroxaban | No | No | Repeat MRI—reduced size with benign features; no surgery | Likely benign | Well at 26 months after presentation |
4 | 44/F | Not reported | No | No | Repeat CT—‘normal’ adrenal; no surgery | Likely benign | Discharged well at 66 months after presentation |
5 | 27/F | Shoulder tip pain, post-partum haemorrhage 6 weeks prior resulting in anemia | US guided drainage after resolution of bleeding | No | Repeat CT—infected collection; further percutaneous drainage and antibiotics done | Likely benign | Well at 6 months after presentation |
6 | 64/F | Not reported | Left adrenal artery embolization | Pheochromocytoma | Repeat CT—persistent lesion; laparoscopic adrenalectomy done | Infarcted tumour—possible phaeochromocytoma |
Well at 7 months after presentation |
7 | 45/F | Not reported | US guided aspiration of collection after resolution of bleeding | No | Repeat CT—recurrent bleeding and progression; open adrenalectomy done for palliation of symptoms and bleeding | Adrenal metastasis (from breast cancer) | Died of metastatic breast cancer 5 months after presentation |
8 | 72/M | Pain radiating to the back, sweating and clamminess, on warfarin | No | No | Subsequent admission for disseminated lung cancer; no surgery | Likely malignant | Died of metastatic lung cancer 2 months after presentation |
9 | 27/F | Associated back pain | No | No | Repeat CT—persistent lesion; laparoscopic adrenalectomy done for persistent pain | Neurilemmoma with cystic degeneration | Well at 12 months after presentation |
10 | 58/M | Not reported | No | No | Repeat MRI—reduced size, but persistent; hand-assist laparoscopic adrenalectomy to establish diagnosis | Cortical hyperplasia | Discharged well at 8 months after presentation |
11 | 41/F | Nausea and vomiting | No | No | Repeat CT—persistent lesion, possibly malignant; open adrenalectomy and nephrectomy done | Oncocytic adrenal cortical neoplasm uncertain malignant potential | Well at 4 months after presentation |