TABLE 1.
Genotype/allele frequency distribution of the AGTR2 rs11091046 polymorphism, among the two ethnic cohorts. (Because AGTR2 is located on the X chromosome, men are hemizygous and contribute a single allele to the genotype).
| Men | Alleles distribution |
||||
|---|---|---|---|---|---|
| A | C | χ2 P value | |||
| Japanese | Athletes (n=158) | 51 (32.3%) | 107 (67.7%) | 0.022* | |
| Controls (n=211) | 93 (44.1%) | 118 (55.9%) | |||
| Russian/Polish | Athletes (n=42) | 16 (38.1%) | 26 (61.9%) | 0.172 | |
| Controls (n=631) | 309 (49.0%) | 322 (51.0%) | |||
| Women |
Genotypes distribution |
||||
| AA | AC | CC | χ2P value | ||
| Japanese | Athletes (n=56) | 4 (7.1%) | 31 (55.4%) | 21 (37.5%) | 0.226 |
| Controls (n=593) | 81 (13.7%) | 268 (45.2%) | 244 (41.1%) | ||
| Russian/Polish | Athletes (n=26) | 4 (15.4%) | 18 (69.2%) | 4 (15.4%) | 0.022* |
| Controls (n=589) | 140 (23.8%) | 248 (42.1%) | 201 (34.1%) | ||