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. 2018 Dec;17(12):1083–1097. doi: 10.1016/S1474-4422(18)30404-6

Table.

Deaths, prevalence, and DALYs for motor neuron disease in 2016 and percentage change of age standardised rates by location

Deaths
Prevalence
DALYs
2016 counts Percentage change in age-standardised rates, 1990–2016 2016 counts Percentage change in age-standardised rates, 1990–2016 2016 counts Percentage change in age-standardised rates, 1990–2016
Global 34 325 (33 051 to 35 364) 8·0% (−0·1 to 12·2) 330 918 (299 522 to 367 254) 4·5% (3·4 to 5·7) 926 090 (881 566 to 961 758) −1·5% (−9·3 to 2·9)
High SDI 21 162 (20 081 to 21 830) 14·1% (5·2 to 19·1) 161 901 (150 024 to 174 346) 19·7% (18·0 to 21·6) 479 748 (455 714 to 496 340) 3·8% (−3·7 to 8·2)
High-middle SDI 4712 (4392 to 4972) 20·7% (2·9 to 31·8) 50 286 (44 798 to 56 819) 16·2% (14·2 to 17·9) 144 696 (134 507 to 153 708) 0·4% (−19·2 to 17·9)
Middle SDI 5183 (4934 to 5387) 22·7% (9·7 to 30·6) 70 924 (61 566 to 82 419) 12·3% (10·3 to 14·0) 177 160 (166 987 to 185 970) 5·7% (−6·0 to 18·0)
Low-middle SDI 2813 (2455 to 3304) 36·7% (11·7 to 57·3) 38 873 (33 761 to 45 357) 10·2% (8·9 to 11·4) 104 268 (93 547 to 119 177) 21·6% (4·8 to 37·3)
Low SDI 443 (382 to 648) 20·2% (−1·8 to 41·9) 8545 (7405 to 10 007) 3·8% (2·8 to 5·0) 19 786 (17 506 to 26 045) 7·1% (−12·9 to 31·5)
High-income North America 8592 (8226 to 8870) 27·2% (19·7 to 32·8) 72 577 (68 184 to 77 282) 7·4% (4·4 to 10·8) 204 447 (195 872 to 212 530) 14·1% (8·0 to 18·9)
Canada 959 (873 to 1045) 20·2% (6·8 to 33·6) 10 013 (9208 to 10 952) 42·1% (35·4 to 49·3) 22 072 (20 194 to 23 900) 12·7% (1·0 to 24·3)
Greenland 0 (0 to 1) 3·3% (−24·6 to 41·1) 8 (7 to 9) 29·8% (25·1 to 35·0) 11 (9 to 14) −1·4% (−24·6 to 27·5)
USA 7632 (7315 to 7902) 27·9% (20·3 to 34·0) 62 531 (58 894 to 66 406) 3·4% (0·1 to 7·2) 182 359 (174 927 to 189 911) 14·3% (8·1 to 19·3)
Australasia 850 (776 to 925) 20·0% (6·9 to 32·3) 5065 (4632 to 5506) 29·4% (25·1 to 33·9) 18 723 (17 236 to 20 191) 11·3% (0·0 to 23·1)
Australia 711 (643 to 779) 21·9% (6·8 to 36·3) 4247 (3886 to 4621) 30·3% (25·4 to 35·4) 15 625 (14 212 to 17 040) 12·7% (−1·1 to 26·1)
New Zealand 139 (122 to 157) 10·8% (−5·6 to 26·5) 818 (747 to 887) 25·1% (19·8 to 30·8) 3097 (2730 to 3465) 3·5% (−10·8 to 18·1)
High-income Asia-Pacific 1919 (1777 to 2055) −9·2% (−15·6 to −2·9) 17 574 (15 713 to 19 782) 18·9% (16·5 to 21·5) 40 294 (37 320 to 43 001) −18·1% (−23·4 to −12·8)
Brunei 1 (0 to 1) 7·3% (−24·0 to 41·3) 19 (17 to 21) 16·2% (12·2 to 20·9) 23 (18 to 28) 7·3% (−20·7 to 38·8)
Japan 1796 (1660 to 1927) −2·5% (−10·2 to 4·5) 13 893 (12 394 to 15 659) 19·9% (17·6 to 22·5) 36 101 (33 402 to 38 439) −11·9% (−18·2 to −6·6)
Singapore 23 (19 to 29) 9·9% (−14·2 to 39·2) 243 (219 to 271) 20·6% (16·0 to 25·1) 718 (592 to 868) −1·2% (−21·0 to 24·5)
South Korea 100 (72 to 130) −33·9% (−55·6 to −8·1) 3419 (3033 to 3860) 26·3% (21·5 to 31·3) 3452 (2658 to 4327) −34·7% (−52·4 to −12·0)
Western Europe 10 357 (9723 to 10 818) 15·2% (3·6 to 22·1) 71 288 (65 330 to 77 548) 31·2% (29·1 to 33·3) 227 135 (213 738 to 237 121) −0·2% (−9·8 to 6·1)
Andorra 2 (2 to 3) 13·2% (−15·4 to 52·2) 15 (14 to 17) 21·0% (16·6 to 25·3) 50 (36 to 62) −0·4% (−23·2 to 30·2)
Austria 152 (136 to 168) 36·8% (20·2 to 54·1) 1282 (1172 to 1405) 36·9% (31·6 to 42·3) 3721 (3367 to 4114) 17·2% (1·0 to 34·7)
Belgium 263 (232 to 293) 24·8% (6·5 to 41·6) 1850 (1699 to 2019) 37·2% (31·8 to 43·4) 5983 (5353 to 6648) 10·9% (−4·9 to 26·9)
Cyprus 13 (11 to 14) −15·4% (−47·2 to 4·2) 108 (98 to 118) 19·7% (14·8 to 24·8) 303 (273 to 336) −27·4% (−55·4 to −5·5)
Denmark 134 (114 to 156) −15·4% (−29·5 to 0·4) 983 (899 to 1078) 20·8% (16·5 to 25·9) 2915 (2487 to 3339) −19·4% (−31·6 to −5·5)
Finland 183 (159 to 204) −23·8% (−38·5 to −9·1) 1207 (1103 to 1319) 19·5% (14·4 to 25·2) 3959 (3455 to 4405) −24·2% (−38·4 to −11·3)
France 1557 (1408 to 1707) 5·0% (−7·5 to 17·7) 11 712 (10 762 to 12 638) 27·3% (22·5 to 32·1) 34 427 (31 349 to 37 585) −6·1% (−17·5 to 5·6)
Germany 1911 (1698 to 2129) 1·3% (−16·3 to 19·9) 12 502 (11 442 to 13 684) 27·5% (22·7 to 32·9) 42 111 (37 875 to 46 516) −9·9% (−26·6 to 6·6)
Greece 111 (96 to 124) 156·3% (104·4 to 202·3) 1141 (1031 to 1256) 29·4% (24·2 to 34·6) 2994 (2620 to 3375) 114·9% (51·4 to 166·4)
Iceland 8 (7 to 9) 23·7% (5·9 to 41·6) 61 (56 to 67) 25·1% (20·2 to 30·2) 188 (169 to 208) 12·8% (−2·6 to 28·6)
Ireland 120 (104 to 138) 24·7% (4·4 to 47·8) 835 (764 to 911) 37·6% (31·6 to 44·0) 2927 (2571 to 3344) 17·9% (−1·5 to 38·5)
Israel 73 (59 to 89) −23·2% (−43·1 to −0·9) 784 (714 to 863) 17·4% (12·7 to 22·1) 1991 (1642 to 2373) −29·6% (−47·2 to −9·8)
Italy 1418 (1 270 to 1 570) 35·8% (18·6 to 54·5) 9553 (8745 to 10 416) 34·5% (28·4 to 40·4) 30 525 (27 281 to 33 409) 9·0% (−6·5 to 26·1)
Luxembourg 9 (8 to 10) 4·4% (−11·4 to 20·3) 86 (79 to 95) 27·2% (22·1 to 32·9) 217 (192 to 245) −7·5% (−21·3 to 6·4)
Malta 8 (7 to 10) 14·5% (−5·9 to 40·8) 62 (56 to 67) 32·2% (26·7 to 37·9) 194 (164 to 233) 15·5% (−4·0 to 38·4)
Netherlands 494 (443 to 554) 7·8% (−7·1 to 22·8) 3347 (3060 to 3648) 28·1% (23·0 to 33·1) 11 110 (9988 to 12 405) −1·4% (−14·5 to 11·8)
Norway 124 (107 to 141) 1·9% (−13·2 to 18·0) 1046 (961 to 1153) 28·0% (22·3 to 33·5) 2764 (2416 to 3125) −8·4% (−21·2 to 5·3)
Portugal 185 (166 to 205) 95·7% (70·3 to 124·7) 1365 (1250 to 1489) 37·6% (31·7 to 43·8) 4639 (4173 to 5106) 48·2% (21·7 to 73·4)
Spain 905 (819 to 991) 41·1% (25·9 to 56·8) 6436 (5888 to 7035) 36·7% (31·0 to 42·3) 20 680 (18 811 to 22 572) 12·1% (−1·0 to 26·0)
Sweden 304 (266 to 344) 35·9% (15·6 to 55·6) 2153 (1944 to 2416) 33·5% (28·7 to 39·3) 6141 (5401 to 897) 25·3% (7·8 to 43·3)
Switzerland 184 (143 to 233) −7·4% (−31·0 to 22·2) 1441 (1314 to 1578) 22·8% (17·9 to 28·3) 3971 (3164 to 4972) −12·9% (−33·9 to 12·7)
United Kingdom 2199 (2075 to 2281) 23·8% (15·5 to 29·3) 13 249 (12 000 to 14 556) 34·5% (31·7 to 37·8) 45 310 (42 802 to 47 187) 0·2% (−6·1 to 4·5)
Southern Latin America 477 (423 to 532) 17·9% (−4·4 to 36·0) 4527 (4103 to 5021) 27·8% (24·7 to 31·1) 12 806 (11 433 to 14 281) 12·6% (−8·3 to 29·1)
Argentina 279 (247 to 309) 29·2% (4·0 to 48·4) 2850 (2576 to 3164) 27·8% (23·6 to 32·5) 7570 (6748 to 8342) 22·0% (−0·3 to 38·8)
Chile 152 (116 to 192) 4·7% (−26·3 to 41·0) 1391 (1253 to 1550) 27·6% (23·3 to 32·1) 4123 (3177 to 5265) 0·2% (−28·0 to 33·8)
Uruguay 47 (42 to 51) −1·5% (−15·5 to 12·7) 285 (261 to 314) 23·4% (18·9 to 28·3) 1112 (998 to 1217) −4·2% (−17·5 to 8·2)
Eastern Europe 729 (583 to 909) 36·1% (6·0 to 72·7) 6497 (5784 to 7341) 3·2% (0·3 to 6·0) 21 974 (17 757 to 27 107) 24·3% (−0·7 to 54·7)
Belarus 33 (26 to 39) 29·3% (4·2 to 56·1) 290 (257 to 329) 5·4% (1·3 to 9·5) 934 (757 to 1 121) 17·7% (−3·3 to 42·2)
Estonia 6 (5 to 7) −1·0% (−16·8 to 14·6) 45 (41 to 51) 2·7% (−0·6 to 6·5) 156 (133 to 177) −12·5% (−26·0 to 1·6)
Latvia 10 (9 to 12) 114·3% (75·3 to 151·7) 66 (59 to 74) 7·0% (3·3 to 10·7) 273 (230 to 312) 85·2% (50·8 to 116·4)
Lithuania 30 (26 to 33) 133·8% (99·8 to 167·1) 121 (110 to 135) 21·3% (15·7 to 26·8) 743 (658 to 824) 105·3% (76·2 to 133·9)
Moldova 9 (8 to 11) 16·9% (−5·7 to 41·9) 100 (88 to 114) 1·1% (−2·4 to 5·1) 297 (254 to 345) 15·9% (−5·4 to 38·2)
Russia 486 (357 to 655) 39·9% (−0·3 to 90·8) 4 587 (4 079 to 5 196) 2·7% (−1·2 to 6·8) 15 218 (11 485 to 20 363) 25·3% (−7·0 to 65·5)
Ukraine 155 (120 to 199) 18·5% (−10·5 to 57·9) 1287 (1141 to 1443) 1·8% (−2·4 to 5·9) 4352 (3386 to 5553) 14·0% (−11·8 to 48·9)
Central Europe 691 (636 to 742) 5·3% (−9·7 to 15·7) 4449 (3998 to 4974) 4·2% (2·1 to 6·5) 19 034 (17 601 to 20 320) −9·3% (−20·9 to −0·3)
Albania 6 (5 to 7) −7·2% (−24·2 to 11·7) 88 (78 to 99) 6·8% (2·5 to 10·9) 192 (161 to 221) −15·0% (−30·7 to 1·4)
Bosnia and Herzegovina 13 (11 to 15) 22·5% (−18·2 to 57·7) 128 (114 to 145) 10·1% (5·6 to 14·8) 373 (317 to 439) 16·6% (−19·6 to 46·4)
Bulgaria 17 (14 to 20) −28·5% (−42·5 to −13·1) 245 (216 to 277) −4·5% (−9·1 to 0·1) 493 (414 to 580) −40·9% (−51·5 to −28·6)
Croatia 38 (32 to 44) 12·1% (−5·7 to 32·3) 179 (161 to 198) −0·4% (−5·0 to 4·8) 1054 (907 to 1202) −6·9% (−21·6 to 10·3)
Czech Republic 77 (69 to 85) 0·5% (−12·9 to 13·8) 443 (397 to 496) −0·8% (−5·1 to 3·8) 2101 (1893 to 2306) −16·1% (−28·7 to −2·1)
Hungary 80 (70 to 90) 0·3% (−14·5 to 16·7) 393 (353 to 438) −1·5% (−6·1 to 3·5) 2289 (2013 to 2578) −18·6% (−32·2 to −1·4)
Macedonia 4 (4 to 5) −52·0% (−62·5 to −40·1) 64 (57 to 72) −5·8% (−10·4 to −0·8) 136 (121 to 151) −70·1% (−78·5 to −58·3)
Montenegro 1 (1 to 1) 3·0% (−14·6 to 23·0) 20 (18 to 23) 4·1% (−0·1 to 8·3) 39 (33 to 44) −5·3% (−19·7 to 11·8)
Poland 346 (307 to 389) 2·9% (−18·9 to 21·2) 1695 (1528 to 1888) 6·5% (2·4 to 10·9) 9135 (8111 to 10 229) −8·7% (−28·0 to 7·5)
Romania 61 (54 to 68) 24·4% (1·4 to 47·1) 639 (566 to 720) 6·4% (2·2 to 10·7) 1825 (1623 to 2047) 8·5% (−12·3 to 29·5)
Serbia 23 (20 to 25) 22·5% (3·9 to 43·3) 288 (256 to 327) 3·9% (−0·5 to 8·3) 662 (595 to 727) 8·9% (−7·2 to 26·0)
Slovakia 21 (17 to 24) 42·5% (13·7 to 69·6) 192 (171 to 217) 6·1% (2·1 to 10·2) 611 (512 to 704) 25·0% (−0·2 to 50·2)
Slovenia 4 (4 to 5) −79·2% (−82·8 to −74·5) 77 (68 to 87) −20·1% (−25·4 to −14·4) 124 (106 to 142) −82·4% (−85·6 to −78·3)
Central Asia 114 (100 to 130) 5·3% (−5·8 to 20·0) 1830 (1612 to 2083) 2·3% (0·6 to 3·9) 4127 (3637 to 4706) −0·5% (−10·0 to 10·0)
Armenia 5 (4 to 5) 5·8% (−12·2 to 24·4) 73 (65 to 83) 3·7% (−0·4 to 7·3) 149 (131 to 168) −2·8% (−17·5 to 13·1)
Azerbaijan 13 (11 to 16) 35·7% (0·5 to 101·2) 215 (190 to 246) 5·2% (1·6 to 9·2) 477 (390 to 575) 24·2% (−5·1 to 78·2)
Georgia 9 (8 to 11) −6·4% (−26·9 to 21·4) 102 (90 to 115) 1·7% (−1·8 to 5·4) 290 (238 to 353) −6·3% (−25·9 to 19·9)
Kazakhstan 34 (23 to 47) −2·2% (−21·6 to 22·5) 417 (366 to 474) 4·0% (0·2 to 8·0) 1180 (836 to 1634) −6·0% (−23·3 to 15·4)
Kyrgyzstan 6 (6 to 7) 3·2% (−16·7 to 30·3) 113 (99 to 129) −0·1% (−3·7 to 3·5) 260 (226 to 293) 1·8% (−17·6 to 27·3)
Mongolia 3 (3 to 4) 38·4% (0·4 to 76·2) 60 (53 to 69) 6·8% (3·1 to 11·0) 121 (102 to 142) 21·2% (−3·5 to 47·0)
Tajikistan 5 (4 to 8) −1·9% (−23·8 to 25·0) 146 (127 to 169) −1·1% (−4·5 to 2·2) 245 (196 to 320) −13·4% (−34·8 to 10·9)
Turkmenistan 8 (6 to 10) 23·9% (−3·1 to 46·9) 107 (94 to 122) 5·7% (1·8 to 9·3) 314 (245 to 380) 11·8% (−12·9 to 33·1)
Uzbekistan 30 (26 to 34) 37·2% (4·7 to 73·7) 597 (524 to 682) 4·0% (0·2 to 8·0) 1091 (949 to 1249) 25·9% (−0·4 to 55·0)
Central Latin America 748 (683 to 791) 57·0% (39·4 to 67·7) 7609 (6627 to 8760) 9·7% (8·3 to 11·1) 23 660 (21 696 to 25 181) 37·1% (23·0 to 45·8)
Colombia 176 (150 to 201) 67·9% (44·4 to 93·6) 1383 (1233 to 1564) 12·4% (8·2 to 16·6) 5306 (4562 to 6054) 41·7% (21·2 to 62·0)
Costa Rica 41 (35 to 46) 47·6% (23·6 to 73·3) 209 (189 to 232) 17·2% (12·5 to 22·2) 1093 (940 to 1239) 48·6% (24·4 to 73·2)
El Salvador 9 (8 to 11) 19·9% (−4·6 to 46·9) 157 (139 to 180) 7·7% (4·0 to 11·8) 296 (250 to 342) 11·9% (−9·1 to 34·6)
Guatemala 16 (12 to 20) 26·6% (−14·9 to 113·6) 367 (319 to 423) 5·7% (2·0 to 9·5) 570 (449 to 717) 19·4% (−16·4 to 88·2)
Honduras 14 (11 to 20) 43·2% (−0·2 to 99·3) 192 (168 to 220) 6·3% (2·4 to 10·5) 501 (375 to 660) 25·5% (−11·0 to 70·5)
Mexico 381 (351 to 405) 64·2% (51·7 to 74·1) 4187 (3577 to 4949) 9·8% (8·1 to 11·7) 12 494 (11 556 to 13 234) 38·7% (28·5 to 46·7)
Nicaragua 8 (6 to 9) 33·6% (−1·3 to 73·1) 148 (130 to 168) 4·2% (0·6 to 8·0) 266 (219 to 316) 20·2% (−6·6 to 51·1)
Panama 12 (10 to 15) 9·8% (−18·0 to 37·0) 117 (104 to 131) 9·4% (5·6 to 13·0) 384 (312 to 450) 9·4% (−16·8 to 35·7)
Venezuela 90 (74 to 108) 28·6% (−4·7 to 67·0) 850 (751 to 966) 5·1% (1·6 to 9·0) 2750 (2235 to 3288) 27·5% (−5·0 to 65·5)
Andean Latin America 114 (98 to 130) 8·3% (−9·9 to 26·0) 1408 (1249 to 1596) 6·5% (4·3 to 9·0) 3564 (3085 to 4013) −1·7% (−18·7 to 14·6)
Bolivia 26 (19 to 34) 24·1% (−28·0 to 72·0) 246 (216 to 281) 7·6% (3·9 to 11·5) 804 (598 to 1047) 11·4% (−36·3 to 51·9)
Ecuador 39 (35 to 44) 60·6% (31·3 to 84·0) 382 (337 to 435) 7·6% (3·8 to 11·0) 1221 (1077 to 1361) 43·5% (16·9 to 63·4)
Peru 49 (39 to 60) −17·5% (−36·1 to 7·6) 779 (691 to 887) 5·6% (2·3 to 9·3) 1539 (1243 to 1855) −24·2% (−41·4 to −0·4)
Caribbean 188 (171 to 204) 3·6% (−9·5 to 19·9) 1481 (1326 to 1657) 2·8% (0·8 to 4·9) 5721 (5093 to 6327) −5·0% (−20·5 to 10·3)
Antigua and Barbuda 0 (0 to 0) −5·7% (−23·1 to 13·6) 3 (3 to 3) 4·9% (1·5 to 8·4) 7 (6 to 8) −4·7% (−20·7 to 12·7)
The Bahamas 2 (2 to 2) −5·2% (−28·1 to 31·6) 14 (13 to 16) −0·2% (−3·8 to 3·3) 59 (51 to 69) −12·5% (−33·6 to 21·4)
Barbados 4 (3 to 4) 12·7% (−5·7 to 36·5) 14 (13 to 15) 4·3% (0·8 to 7·8) 95 (84 to 107) 12·0% (−6·5 to 37·2)
Belize 1 (1 to 1) 136·6% (46·9 to 229·1) 10 (9 to 11) 9·8% (5·6 to 13·6) 33 (25 to 43) 89·1% (23·8 to 167·1)
Bermuda 0 (0 to 0) −36·5% (−53·5 to −13·5) 3 (3 to 4) −5·4% (−8·9 to −1·9) 11 (8 to 13) −41·5% (−55·6 to −18·2)
Cuba 91 (81 to 101) −2·6% (−17·8 to 18·5) 502 (449 to 559) 2·7% (−1·3 to 6·8) 2500 (2228 to 2769) −11·1% (−24·1 to 6·7)
Dominica 1 (0 to 1) 50·4% (4·7 to 88·4) 3 (2 to 3) 13·8% (10·1 to 18·4) 16 (14 to 19) 51·9% (7·4 to 89·6)
Dominican Republic 16 (13 to 20) 13·7% (−23·7 to 45·7) 303 (268 to 344) 8·5% (4·8 to 12·6) 529 (428 to 631) 0·3% (−30·0 to 26·3)
Grenada 1 (0 to 1) 72·9% (20·0 to 148·8) 3 (3 to 4) 13·6% (9·1 to 18·0) 16 (13 to 19) 64·5% (16·1 to 133·6)
Guyana 2 (2 to 3) −1·5% (−22·9 to 20·6) 18 (16 to 21) 9·0% (5·1 to 13·3) 72 (59 to 86) −8·5% (−27·5 to 12·4)
Haiti 23 (16 to 31) 16·6% (−31·3 to 62·3) 225 (196 to 260) 2·8% (−0·6 to 6·3) 957 (633 to 1 391) −1·7% (−45·3 to 45·8)
Jamaica 11 (9 to 14) 45·5% (4·1 to 92·6) 91 (81 to 102) 5·8% (1·8 to 9·8) 424 (318 to 568) 31·7% (−12·2 to 87·8)
Puerto Rico 24 (21 to 27) 16·2% (−6·9 to 39·6) 156 (141 to 174) 8·0% (4·1 to 11·5) 636 (555 to 709) 5·7% (−14·7 to 25·7)
Saint Lucia 1 (1 to 1) 61·5% (15·4 to 124·7) 6 (6 to 7) 14·8% (10·8 to 19·2) 33 (30 to 37) 50·8% (8·1 to 106·5)
Saint Vincent and the Grenadines 1 (1 to 1) 176·2% (136·0 to 228·0) 4 (3 to 4) 13·1% (9·1 to 17·0) 19 (17 to 21) 131·0% (86·8 to 178·2)
Suriname 2 (2 to 2) 55·8% (27·8 to 85·3) 15 (13 to 17) 10·0% (6·0 to 14·1) 65 (56 to 75) 39·5% (14·7 to 68·3)
Trinidad and Tobago 7 (6 to 7) 6·5% (−16·4 to 29·3) 46 (41 to 52) 7·8% (4·0 to 12·0) 197 (173 to 221) 10·0% (−13·5 to 35·0)
Virgin Islands 2 (1 to 2) 58·9% (21·5 to 95·1) 6 (6 to 7) 18·1% (13·4 to 23·5) 39 (32 to 46) 45·6% (12·1 to 80·1)
Tropical Latin America 1155 (1073 to 1219) 79·1% (60·0 to 90·1) 8125 (7084 to 9365) 20·0% (17·2 to 23·1) 33 632 (31 235 to 35 552) 57·7% (40·5 to 68·1)
Brazil 1132 (1051 to 1197) 77·3% (58·9 to 88·3) 7919 (6904 to 9132) 20·3% (17·4 to 23·5) 32 909 (30 585 to 34 846) 56·2% (39·4 to 66·6)
Paraguay 23 (19 to 26) 215·4% (120·4 to 311·1) 206 (184 to 233) 10·8% (6·8 to 14·9) 723 (610 to 834) 177·6% (101·4 to 253·5)
East Asia 3097 (2956 to 3234) −1·3% (−12·4 to 16·3) 56 465 (48 633 to 65 987) 18·2% (15·3 to 20·9) 111 827 (104 988 to 118 511) −11·6% (−22·7 to 13·2)
China 2988 (2839 to 3122) −1·1% (−12·4 to 17·4) 54 405 (46 781 to 63 692) 18·6% (15·6 to 21·4) 107 731 (100 956 to 114 351) −12·1% (−23·8 to 13·8)
North Korea 60 (43 to 96) 14·6% (−6·1 to 43·8) 955 (847 to 088) 2·6% (−0·9 to 6·0) 2477 (1814 to 3998) 12·6% (−11·9 to 45·5)
Taiwan (province of China) 49 (40 to 57) −28·0% (−44·3 to −12·3) 1104 (981 to 1253) 13·5% (9·2 to 17·5) 1619 (1354 to 1881) −22·9% (−38·2 to −8·1)
Southeast Asia 903 (770 to 997) 25·2% (0·5 to 37·0) 16 378 (14 345 to 18 910) 10·4% (9·2 to 11·6) 33 240 (28 726 to 36 864) 10·5% (−5·9 to 20·4)
Cambodia 15 (11 to 19) 36·7% (−0·1 to 74·7) 316 (278 to 362) 10·6% (7·0 to 14·3) 622 (457 to 783) 20·6% (−13·0 to 58·5)
Indonesia 335 (232 to 397) 43·1% (24·6 to 59·8) 6151 (5193 to 7307) 10·6% (9·0 to 12·4) 12 963 (9505 to 15 281) 17·0% (2·5 to 38·1)
Laos 7 (5 to 10) 24·9% (−11·7 to 79·0) 142 (124 to 163) 11·1% (7·4 to 15·2) 390 (242 to 652) 10·1% (−28·4 to 70·3)
Malaysia 43 (33 to 49) 23·8% (−17·2 to 54·9) 814 (722 to 925) 8·6% (4·9 to 12·4) 1541 (1236 to 1761) 17·8% (−18·4 to 44·5)
Maldives 0 (0 to 0) −24·4% (−48·9 to 21·6) 8 (7 to 10) 8·7% (5·3 to 12·5) 13 (11 to 16) −34·7% (−55·7 to 11·8)
Mauritius 3 (3 to 4) 2·7% (−14·7 to 21·5) 41 (37 to 47) 8·6% (5·4 to 12·9) 103 (89 to 121) −3·5% (−18·6 to 13·7)
Myanmar 110 (93 to 131) 26·7% (−13·7 to 60·1) 1285 (1139 to 1465) 13·3% (9·3 to 17·4) 3879 (3307 to 4615) 17·6% (−16·1 to 49·6)
Philippines 102 (79 to 124) 17·0% (−11·3 to 44·4) 2309 (2034 to 2655) 6·7% (3·3 to 10·2) 3903 (3142 to 4678) 2·5% (−19·9 to 24·7)
Sri Lanka 40 (32 to 51) 21·6% (−16·3 to 62·9) 593 (523 to 674) 9·6% (6·0 to 13·0) 1360 (1074 to 1677) −0·2% (−32·6 to 40·2)
Seychelles 0 (0 to 0) 0·6% (−24·5 to 24·7) 3 (2 to 3) 7·5% (4·0 to 11·2) 7 (5 to 8) −3·8% (−26·8 to 17·2)
Thailand 123 (106 to 142) −3·4% (−26·3 to 17·7) 2166 (1911 to 2458) 10·0% (6·7 to 13·7) 4091 (3555 to 4724) −7·3% (−27·7 to 11·9)
Timor–Leste 1 (1 to 1) 39·7% (−12·3 to 136·9) 23 (20 to 26) 13·6% (10·0 to 17·3) 39 (27 to 55) 11·5% (−30·4 to 94·6)
Vietnam 123 (99 to 153) 28·3% (−6·5 to 69·3) 2504 (2209 to 2846) 11·4% (7·8 to 15·6) 4324 (3536 to 5319) 14·0% (−13·6 to 46·4)
Oceania 13 (10 to 18) −5·7% (−21·2 to 12·4) 212 (187 to 244) 4·0% (1·6 to 6·5) 467 (384 to 621) −3·8% (−19·4 to 15·3)
American Samoa 0 (0 to 0) −22·1% (−42·3 to −0·3) 2 (2 to 2) 0·0% (−3·6 to 3·8) 5 (4 to 6) −19·2% (−39·4 to 2·8)
Federated States of Micronesia 0 (0 to 0) 23·7% (−21·4 to 72·2) 2 (2 to 2) 6·4% (2·8 to 10·4) 8 (6 to 11) 22·0% (−19·7 to 71·1)
Fiji 2 (1 to 2) 33·5% (−14·7 to 88·8) 22 (19 to 25) 7·0% (3·5 to 10·5) 52 (40 to 66) 31·3% (−11·1 to 82·3)
Guam 1 (1 to 1) −45·2% (−56·6 to −30·4) 6 (6 to 7) −16·3% (−20·2 to −12·5) 30 (24 to 35) −42·6% (−54·6 to −27·4)
Kiribati 0 (0 to 0) 46·4% (10·2 to 95·3) 2 (2 to 2) 4·7% (1·4 to 8·4) 9 (7 to 12) 46·0% (10·7 to 96·7)
Marshall Islands 0 (0 to 0) 0·9% (−27·8 to 29·8) 1 (1 to 2) 4·7% (0·9 to 8·2) 4 (3 to 6) 1·1% (−25·3 to 28·8)
Northern Mariana Islands 0 (0 to 0) 43·9% (2·4 to 97·0) 3 (3 to 4) 5·5% (2·1 to 9·2) 8 (6 to 11) 30·4% (−6·9 to 78·5)
Papua New Guinea 8 (5 to 12) −1·3% (−22·4 to 30·4) 135 (118 to 156) 6·9% (3·2 to 10·7) 290 (203 to 424) −2·6% (−23·6 to 27·6)
Samoa 0 (0 to 1) −7·6% (−26·6 to 19·1) 5 (4 to 5) 5·8% (2·4 to 9·4) 10 (7 to 17) −6·6% (−25·4 to 19·0)
Solomon Islands 1 (1 to 1) 6·6% (−17·0 to 44·9) 11 (9 to 13) 5·4% (1·6 to 8·9) 27 (21 to 40) 9·5% (−15·2 to 49·2)
Tonga 0 (0 to 0) −1·4% (−25·5 to 29·2) 3 (2 to 3) 5·4% (2·2 to 9·1) 6 (5 to 8) 0·1% (−22·7 to 30·8)
Vanuatu 0 (0 to 1) 14·3% (−15·7 to 52·6) 6 (5 to 6) 5·3% (1·7 to 8·9) 15 (12 to 23) 17·2% (−13·3 to 56·3)
North Africa and Middle East 1139 (964 to 1276) 5·7% (−23·6 to 24·5) 13 291 (11 746 to 15 182) 3·1% (1·7 to 4·4) 45 475 (38 290 to 51 031) −14·3% (−40·1 to 9·3)
Afghanistan 37 (21 to 59) 31·8% (4·2 to 71·9) 517 (444 to 603) 3·2% (−0·8 to 7·0) 1689 (945 to 2676) 22·7% (−3·3 to 59·7)
Algeria 60 (51 to 70) 6·9% (−16·4 to 32·5) 943 (832 to 1 079) 2·9% (−1·4 to 7·0) 2332 (1961 to 2736) −8·6% (−31·9 to 16·7)
Bahrain 1 (1 to 2) −7·6% (−31·9 to 21·7) 36 (31 to 42) 4·1% (0·4 to 8·3) 60 (47 to 76) −10·5% (−32·2 to 17·0)
Egypt 168 (102 to 217) 29·6% (−1·6 to 62·3) 1908 (1682 to 2185) 7·1% (3·0 to 11·6) 6211 (3881 to 7959) 7·4% (−16·1 to 33·7)
Iran 106 (86 to 129) 84·9% (19·8 to 175·5) 2012 (1781 to 2283) 7·3% (3·3 to 11·7) 3839 (3181 to 4608) 58·6% (9·7 to 120·1)
Iraq 36 (28 to 46) 25·3% (−13·8 to 72·9) 782 (676 to 907) 3·6% (−0·2 to 7·5) 1684 (1287 to 2256) 17·1% (−16·8 to 60·1)
Jordan 9 (7 to 11) 39·2% (−18·7 to 106·4) 174 (153 to 200) 4·5% (0·5 to 9·0) 431 (338 to 530) 42·3% (−11·0 to 99·7)
Kuwait 5 (4 to 7) −21·0% (−43·4 to 10·9) 116 (102 to 134) −0·3% (−4·2 to 3·9) 263 (198 to 346) −29·3% (−47·6 to −1·7)
Lebanon 8 (5 to 11) −27·7% (−65·6 to 8·0) 159 (140 to 179) 3·2% (−1·0 to 7·2) 273 (182 to 360) −32·4% (−66·2 to 0·9)
Libya 15 (8 to 20) 40·9% (−4·5 to 84·2) 150 (132 to 172) −3·8% (−7·5 to 0·2) 560 (317 to 731) 22·3% (−11·8 to 59·6)
Morocco 47 (38 to 55) 42·2% (13·6 to 72·3) 783 (690 to 896) 5·1% (1·3 to 9·1) 1733 (1418 to 2051) 21·6% (−2·6 to 50·1)
Oman 5 (3 to 7) 75·1% (0·5 to 271·7) 108 (94 to 125) 7·2% (3·4 to 11·2) 203 (142 to 279) 43·3% (−10·6 to 156·2)
Palestine 4 (3 to 5) 9·5% (−19·2 to 44·7) 102 (88 to 118) 3·0% (−0·7 to 7·2) 179 (153 to 214) −16·4% (−39·9 to 17·6)
Qatar 2 (1 to 3) −3·9% (−37·6 to 48·3) 62 (53 to 71) 4·4% (0·1 to 8·9) 92 (67 to 122) −10·0% (−39·0 to 32·9)
Saudi Arabia 42 (32 to 51) 88·1% (10·5 to 197·3) 854 (717 to 1 022) 7·1% (5·1 to 9·1) 1683 (1305 to 1997) 48·2% (−8·7 to 114·8)
Sudan 39 (25 to 51) 34·0% (8·6 to 64·6) 618 (540 to 719) 6·9% (2·8 to 10·8) 1882 (1092 to 2694) 21·6% (−8·3 to 64·1)
Syria 19 (15 to 23) 23·4% (−21·5 to 75·4) 413 (361 to 477) 4·0% (−0·1 to 8·3) 741 (627 to 894) 5·6% (−34·4 to 44·3)
Tunisia 19 (14 to 23) 15·6% (−22·2 to 54·7) 298 (263 to 339) 5·1% (0·8 to 8·8) 669 (530 to 820) −3·1% (−38·2 to 27·2)
Turkey 470 (392 to 566) −18·9% (−52·2 to 16·3) 2554 (2274 to 2864) −1·5% (−5·7 to 2·6) 18 887 (15 336 to 23 603) −36·1% (−64·3 to 16·7)
United Arab Emirates 26 (14 to 37) 67·0% (−4·0 to 170·1) 266 (231 to 306) 1·7% (−1·9 to 6·0) 1082 (614 to 1552) 49·8% (−12·2 to 139·8)
Yemen 21 (15 to 29) 40·1% (−0·3 to 100·8) 420 (365 to 483) 5·1% (1·0 to 9·1) 982 (665 to 1356) 20·8% (−13·6 to 68·4)
South Asia 2711 (2231 to 3277) 48·9% (18·0 to 76·6) 32 104 (27 566 to 37 755) 14·2% (12·8 to 15·7) 95 154 (80 575 to 109 736) 35·7% (12·3 to 55·2)
Bangladesh 146 (104 to 240) −25·6% (−46·2 to 4·4) 2851 (2501 to 3272) 8·6% (5·0 to 12·5) 5726 (4307 to 8582) −29·6% (−49·4 to 6·8)
Bhutan 1 (1 to 2) 30·2% (−8·1 to 75·0) 15 (14 to 18) 11·8% (7·7 to 15·7) 40 (31 to 57) 11·7% (−21·8 to 54·5)
India 2309 (1894 to 2726) 56·9% (21·4 to 86·5) 25 276 (21 450 to 30 120) 16·1% (14·6 to 17·6) 79 261 (66 554 to 90 980) 44·0% (15·8 to 65·0)
Nepal 33 (23 to 57) 45·8% (4·8 to 125·7) 514 (449 to 592) 8·1% (4·4 to 12·7) 1177 (848 to 1929) 25·4% (−9·3 to 104·3)
Pakistan 223 (175 to 311) 66·4% (18·0 to 133·3) 3448 (3020 to 3988) 7·0% (3·3 to 10·8) 8950 (7142 to 12 333) 48·5% (11·2 to 95·9)
Southern sub-Saharan Africa 73 (67 to 79) 31·4% (6·3 to 55·4) 1114 (957 to 1317) 4·7% (3·4 to 6·2) 2617 (2391 to 2838) 23·4% (2·6 to 43·5)
Botswana 2 (1 to 3) 42·5% (−33·1 to 133·9) 31 (27 to 36) 6·6% (3·1 to 10·1) 80 (37 to 119) 41·8% (−32·3 to 129·7)
Lesotho 2 (1 to 3) 108·8% (0·0 to 214·2) 26 (22 to 30) 6·5% (2·7 to 10·2) 63 (44 to 89) 106·2% (2·0 to 206·7)
Namibia 2 (1 to 2) 10·7% (−30·6 to 58·7) 32 (28 to 37) 4·8% (1·2 to 8·1) 63 (43 to 88) 9·0% (−29·8 to 51·3)
South Africa 55 (50 to 59) 29·3% (1·9 to 49·7) 841 (711 to 1 003) 5·9% (4·4 to 7·5) 1932 (1769 to 2108) 19·8% (−2·6 to 37·4)
Swaziland 1 (0 to 1) 30·0% (−19·4 to 101·8) 16 (14 to 19) 5·0% (1·5 to 8·8) 31 (20 to 45) 31·6% (−15·9 to 97·2)
Zimbabwe 12 (9 to 15) 38·2% (−4·2 to 153·8) 168 (145 to 197) −1·4% (−4·7 to 1·7) 449 (356 to 574) 33·2% (−5·8 to 126·9)
Western sub-Saharan Africa 273 (220 to 330) 16·6% (−8·0 to 36·8) 4075 (3541 to 4754) 4·5% (2·7 to 6·1) 13 364 (8976 to 16 996) 7·8% (−17·8 to 28·8)
Benin 8 (6 to 10) 22·9% (−8·6 to 63·8) 114 (99 to 133) 3·4% (0·0 to 7·3) 336 (276 to 424) 8·3% (−22·5 to 43·6)
Burkina Faso 11 (9 to 14) 23·8% (−7·4 to 73·5) 175 (152 to 205) 5·1% (1·8 to 8·5) 545 (417 to 731) 17·2% (−11·8 to 61·9)
Cameroon 22 (15 to 28) 40·0% (−0·5 to 82·3) 235 (203 to 274) 1·5% (−1·5 to 4·5) 1004 (594 to 1407) 37·8% (−0·7 to 79·4)
Cape Verde 0 (0 to 1) 71·8% (18·9 to 124·7) 8 (7 to 9) 8·2% (4·5 to 11·9) 18 (15 to 21) 53·1% (15·3 to 95·7)
Chad 8 (6 to 11) 11·7% (−14·0 to 39·4) 140 (121 to 164) 5·2% (2·0 to 8·4) 438 (265 to 636) 10·7% (−14·9 to 39·2)
Côte d'Ivoire 23 (18 to 28) 24·2% (−7·1 to 58·9) 230 (201 to 270) 1·4% (−1·9 to 4·7) 951 (681 to 1197) 20·4% (−10·5 to 53·3)
The Gambia 1 (1 to 1) 5·1% (−16·9 to 30·9) 21 (18 to 25) 1·3% (−2·1 to 4·4) 51 (41 to 65) −1·0% (−20·9 to 21·5)
Ghana 31 (24 to 40) 53·6% (17·4 to 147·2) 309 (269 to 357) 6·2% (2·8 to 9·8) 1186 (924 to 1531) 42·8% (8·0 to 119·1)
Guinea 9 (7 to 12) 29·8% (−12·3 to 87·6) 126 (109 to 146) 0·9% (−2·4 to 4·2) 380 (296 to 546) 11·8% (−26·7 to 62·7)
Guinea-Bissau 2 (1 to 2) 18·2% (−11·2 to 67·0) 19 (16 to 22) 2·0% (−1·4 to 5·2) 71 (54 to 97) 9·8% (−15·2 to 52·2)
Liberia 3 (2 to 3) 5·6% (−28·2 to 35·1) 43 (37 to 51) 0·4% (−2·6 to 3·8) 107 (87 to 137) −10·1% (−42·0 to 17·3)
Mali 8 (6 to 12) −5·7% (−34·7 to 40·1) 178 (154 to 209) 6·2% (3·1 to 9·4) 430 (327 to 594) −13·0% (−39·8 to 33·2)
Mauritania 3 (2 to 4) −6·1% (−32·3 to 24·6) 51 (44 to 59) 3·3% (0·0 to 6·7) 125 (80 to 166) −3·9% (−29·6 to 27·0)
Niger 9 (7 to 14) −5·0% (−35·3 to 51·5) 190 (165 to 223) 1·8% (−1·1 to 4·7) 450 (340 to 649) −19·5% (−47·5 to 37·1)
Nigeria 112 (67 to 152) 4·3% (−34·5 to 38·5) 1936 (1687 to 2255) 6·0% (2·3 to 9·3) 6316 (3210 to 9266) −1·8% (−39·0 to 32·5)
São Tomé and Príncipe 0 (0 to 0) 26·8% (−13·4 to 162·6) 2 (2 to 2) 2·8% (−0·4 to 6·2) 5 (3 to 9) 9·3% (−26·0 to 110·0)
Senegal 12 (9 to 14) 16·8% (−6·2 to 46·3) 164 (141 to 190) 2·1% (−1·3 to 5·5) 485 (398 to 592) 8·4% (−14·4 to 36·4)
Sierra Leone 5 (3 to 6) 13·6% (−12·8 to 49·5) 62 (54 to 73) 2·8% (−0·2 to 6·0) 223 (133 to 317) −2·0% (−27·7 to 29·1)
Togo 6 (4 to 8) 19·7% (−21·1 to 60·8) 73 (63 to 85) 1·1% (−2·6 to 4·4) 245 (154 to 337) 13·2% (−26·2 to 47·8)
Eastern sub-Saharan Africa 131 (104 to 214) 6·7% (−18·4 to 36·3) 3762 (3258 to 4423) 3·6% (2·5 to 4·8) 6471 (5350 to 9325) −6·4% (−29·3 to 29·7)
Burundi 4 (3 to 7) −20·9% (−41·5 to 13·8) 98 (84 to 115) 0·7% (−2·7 to 3·8) 208 (140 to 342) −23·5% (−43·3 to 14·4)
Comoros 0 (0 to 1) −3·8% (−29·9 to 25·9) 9 (7 to 10) −0·1% (−3·3 to 3·4) 15 (11 to 22) −11·2% (−34·9 to 18·1)
Djibouti 0 (0 to 1) 23·6% (−15·4 to 87·1) 11 (10 to 13) −0·1% (−3·2 to 2·7) 23 (16 to 33) 2·5% (−30·9 to 45·0)
Eritrea 2 (1 to 3) 17·2% (−18·3 to 66·2) 55 (47 to 64) 3·8% (0·0 to 7·6) 93 (71 to 139) 10·4% (−20·0 to 49·9)
Ethiopia 31 (22 to 61) −8·5% (−40·0 to 54·1) 987 (857 to 1153) 3·9% (0·6 to 7·2) 1375 (1012 to 2365) −18·5% (−48·2 to 44·2)
Kenya 15 (12 to 21) 44·15% (3·2 to 85·8) 515 (422 to 628) 3·1% (2·2 to 4·0) 731 (593 to 925) 25·0% (−2·5 to 49·1)
Madagascar 8 (5 to 14) −4·6% (−35·0 to 30·4) 272 (236 to 316) 0·4% (−2·7 to 3·7) 405 (294 to 595) −12·2% (−40·5 to 16·5)
Malawi 6 (4 to 11) 15·2% (−23·8 to 73·4) 164 (142 to 193) 2·1% (−1·0 to 5·4) 329 (226 to 515) −9·8% (−41·6 to 49·5)
Mozambique 10 (6 to 19) −0·4% (−29·7 to 32·4) 284 (246 to 333) 7·1% (3·8 to 10·7) 501 (348 to 787) −12·3% (−39·0 to 23·6)
Rwanda 3 (2 to 8) 6·2% (−40·9 to 67·3) 110 (95 to 129) 2·9% (−0·2 to 6·3) 174 (102 to 388) −2·2% (−41·2 to 56·6)
Somalia 3 (2 to 6) −5·6% (−28·9 to 25·6) 93 (80 to 108) 0·1% (−3·2 to 3·4) 157 (108 to 270) −16·1% (−39·1 to 16·3)
South Sudan 4 (2 to 7) −1·5% (−26·8 to 31·7) 131 (114 to 153) 0·6% (−2·2 to 3·6) 198 (127 to 332) −16·5% (−39·5 to 18·7)
Tanzania 23 (16 to 40) 11·4% (−12·3 to 43·6) 527 (455 to 615) 4·0% (0·7 to 7·4) 1170 (858 to 1765) −3·4% (−28·3 to 28·0)
Uganda 11 (8 to 21) 17·3% (−43·2 to 112·1) 342 (294 to 407) 5·9% (2·4 to 9·3) 628 (443 to 1040) 6·8% (−48·6 to 78·1)
Zambia 10 (7 to 14) 54·2% (3·8 to 123·4) 162 (140 to 190) 3·3% (−0·1 to 7·0) 465 (318 to 666) 15·0% (−23·2 to 70·1)
Central sub-Saharan Africa 40 (29 to 65) −0·5% (−16·0 to 19·5) 1086 (943 to 1273) 0·8% (−1·3 to 2·9) 2007 (1483 to 2934) −8·8% (−28·2 to 17·1)
Angola 9 (6 to 16) 18·6% (−22·7 to 81·6) 263 (228 to 308) 5·0% (1·8 to 8·4) 497 (339 to 788) 9·3% (−24·8 to 69·3)
Central African Republic 2 (2 to 4) 5·3% (−20·1 to 36·6) 44 (38 to 52) −0·6% (−3·9 to 2·7) 103 (67 to 159) −0·2% (−25·6 to 32·0)
Congo (Brazzaville) 3 (2 to 4) −9·9% (−37·5 to 20·3) 48 (41 to 55) 3·2% (−0·1 to 6·9) 115 (80 to 161) −11·6% (−38·5 to 16·6)
Democratic Republic of the Congo 24 (16 to 43) −4·5% (−23·2 to 14·4) 702 (606 to 823) −1·1% (−4·2 to 1·7) 1222 (826 to 1861) −14·5% (−36·8 to 13·5)
Equatorial Guinea 0 (0 to 1) 0·3% (−43·4 to 75·5) 9 (8 to 11) 24·6% (19·9 to 29·5) 20 (13 to 31) −14·9% (−51·6 to 58·0)
Gabon 1 (1 to 2) 10·1% (−22·4 to 51·3) 21 (18 to 24) 2·0% (−1·5 to 5·7) 50 (37 to 66) 3·4% (−27·8 to 41·2)

95% uncertainty intervals are in parentheses. DALYs=disability-adjusted life-years. SDI=Socio-demographic Index.