Fig. 2.

Stress and CNR1 genotype effects on brain activity during affective picture processing. (A) Activity in the vmPFC was increased in rs1049353 AA/AG compared to GG genotype carriers for negative (vs neutral) picture processing under stress. (B) Under no-stress control conditions, the vlPFC showed enhanced functional connectivity with the amygdala when AA/AG compared to GG genotype carriers viewed negative (vs neutral) pictures. Activations are superimposed on coronal sections of a T1-weighted template image and represented in red. vmPFC: ventromedial prefrontal cortex, vlPFC: ventrolateral prefrontal cortex, L corresponds to the left, R to the right side of the brain and error bars represent SEM. ^**P < 0.01