Table 1.

Subjective stress response

	Control		Stress
	AA/AG genotype	GG genotype	AA/AG genotype	GG genotype
Subjective assessment
Stressful	24.64 ± 4.07	31.03 ± 3.36	64.12 ± 3.56	67.43 ± 3.49***
Difficult	25.71 ± 4.32	26.41 ± 3.30	70.88 ± 4.01	71.14 ± 3.40***
Unpleasant	28.93 ± 4.78	37.69 ± 3.93	66.18 ± 4.35	70.57 ± 3.50***
Subjective mood
Good vs bad mood
Before treatment	33.86 ± 0.71	34.45 ± 0.82	34.38 ± 0.73	34.43 ± 0.65
1 min after treatment	32.64 ± 0.82	34.15 ± 0.78	28.15 ± 1.13	27.91 ± 1.16***
75 min after treatment	32.14 ± 0.96	32.85 ± 0.81	30.35 ± 1.09	31.31 ± 0.82
Calm vs restless
Before treatment	29.93 ± 0.96	33.26 ± 0.84	30.97 ± 0.98	32.60 ± 0.71
1 min after treatment	29.11 ± 1.03	31.38 ± 0.91	23.76 ± 1.15	24.79 ± 1.07***
75 min after treatment	30.68 ± 0.88	32.00 ± 0.98	31.59 ± 0.98	31.80 ± 0.67
Overall calm vs restless	29.90 ± 0.78	32.13 ± 0.79	28.77 ± 0.86	29.82 ± 0.58#
Tired vs awake
Before treatment	29.93 ± 1.07	30.76 ± 0.98	30.03 ± 0.78	30.43 ± 0.85
1 min after treatment	28.82 ± 1.13	30.10 ± 0.99	28.82 ± 0.95	28.24 ± 0.88
75 min after treatment	22.93 ± 0.97	24.26 ± 1.00	21.38 ± 1.01	23.51 ± 0.97

Data represent means ± SEM.

Time × Treatment (stress vs control) ^***P < 0.001 ^**P < 0.01 ^*P < 0.05

CNR1 genotype (AA/AG vs GG) ^#P < 0.05