Table 3.

Prognostic factor for overall survival according to disease extent in univariate analysis (log rank test)

Characteristic	Localized disease			Systemic disease
	Number (n = 98)	Median OS, ms	Univariate p value	Number (n = 50)	Median OS, ms	Univariate p value
Age, yr			0.230			0.517
80–84	74	52.0		33	5.4
85–89	17	26.8		12	7.2
≥ 90	7	93.9		5	3.9
Sex			0.018a			0.617
Female	47	103.9		28	4.5
Male	51	37.2		22	7.0
Primary tumor site			0.226			0.144
Ascending colon	23	45.4		18	7.5
Transverse colon	5	24.8		1	1.1
Descending colon	39	65.9		17	7.2
Rectum	31	25.6		14	3.5
Performance status (ECOG)			0.000a			0.000a
0–1	68	84.9		29	11.0
2–4	30	14.8		21	2.6
Treatment
Cancer treatment			0.000a			0.001a
Yes	81	76.2		28	9.9
No	17	15.4		22	2.6
Operation			0.000a			0.017a
Yes	79	80.2		16	10.7
No	19	15.4		34	3.5
Chemotherapy	Adjuvant		0.109	Palliative		0.000a
Yes	42	65.9		24	11.6
No	56	38.2		26	2.6
Initial CEA			0.119			0.736
Normal	60	69.5		6	6.9
Elevated	25	31.3		32	7.2
Unavailable	13			12
BMI			0.000a			0.402
< 20	13	24.8		11	4.5
≤ 20 and < 25	44	69.5		17	11.0
≥ 25	20	109.1		5	8.0
Unavailable	21			17
Comorbidities			0.620			0.831
No disease	26	65.9		20	5.4
1 Comorbid	38	31.0		17	5.2
≥ 2 Comorbid	34	38.2		13	6.9
Unavailable

OS, overall survival; ECOG, Eastern Cooperative Oncology Group; CEA, carcinoembryonic antigen; BMI, body mass index.

^ap < 0.05.