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Reduced oscillation of the PK2 expression in the SCN of the PKR2-PK2 transgenic mice. Panel A shows the representative images of PK2 mRNA expression in the SCN of the wild type mice (WT) and the PKR2-PK2 transgenic mice (TG14). Panel B shows the temporal profiles of quantified PK2 mRNA levels in the SCN. Note the increased PK2 during the subjective dark period, particularly CT17 and CT21, in the transgenic mice. Scale bar, 1 mm.
