Table 2.
LH concentrations before and after intranasal insulin or saline administration in healthy lean men.
| Lean | Insulin | Saline | Mean difference (95% confidence interval) | p | ||||
|---|---|---|---|---|---|---|---|---|
| Baseline (0–120 minutes) | Posttreatment (135–300 minutes) | p | Mean baseline LH (0–120 minutes) | Mean LH after treatment (135–300 minutes) | p | |||
| Mean LH (IU/l) | 3.3 ± 1.4 | 3.4 ± 1.2 | 0.76 | 3.6 ± 0.9 | 3.8 ± 1.4 | 0.63 | −0.1, [−1.1, 0.9] | 0.83 |
| Peak LH (IU/l) | 4.6 ± 2.0 | 5.0 ± 1.4 | 0.51 | 5.3 ± 1.8 | 5.4 ± 1.9 | 0.92 | −0.1, [−1.7, 1.5] | 0.89 |
| Number of LH pulses (per hour) | 0.4 ± 0.2 | 0.4 ± 0.4 | 0.87 | 0.3 ± 0.3 | 0.3 ± 0.4 | 0.99 | 0.0, [−0.5, 0.5] | 0.90 |
| Glucose (mmol/l) | 5.2 ± 0.7 | 4.9 ± 0.4 | 0.37 | 5.2 ± 0.5 | 5.1 ± 0.2 | 0.41 | −0.1, [−1, 0.8] | 0.74 |
The penultimate column shows the mean difference between the two treatments.