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. 2018 Nov 9;9:54–60. doi: 10.1515/tnsci-2018-0010

Table 1.

Comparison of studies of the effect of resveratrol on tau in mice

Factor Porquet [15] Varamini [16] Yu (this paper)
Model SAMP8 wildtype; APP/PS JNPL3
# of mice 10-12 v. 10-12 3 v. 6; 6 v. 3 9 v. 8
Age 2 months 12 months 11 months
Duration 7 months 4 months 3 months
Dose ~0.09 mg/g, daily ~0.17 mg/g, daily 0.10mg/g, 5 times/wk
Assay ptau v. tau blot ptau v. tau blot ptau sections ptau v. tau blot
Fraction 10k g supernatant 13k g supernatant all PHF
Effect Decrease no change decrease no change