Table 2: Risk Score After Treatment and at Follow-up.
| Risk Score | Clinical Setting | Time of Score Use | Predicted Event | Parameters | C-statistic (Derived/External Validation) | Trials/Studies (Reference) |
|---|---|---|---|---|---|---|
| CADILLAC risk score | ACS | Post-PCI | 1-year mortality | Clinical: 2 Echocardiographic: 1 Laboratory: 2 Angiographic: 1 cTherapeutic: 1 |
0.79/0.78 | 22,23,24,25 |
| PAMI risk score | ACS | Post-primary PCI | 6-month mortality | Clinical: 3 Electrocardiographic: 1 |
0.78/NR | 23,26,27,28 |
| ZWOLLE risk score | STEMI | Post-primary PCI | 30-day mortality | Clinical: 3 Angiographic: 3 |
0.902/0.937 | 29,30,31,32 |
| GRACE hospital discharge score | All subset of ACS | Pre-discharge | All-cause mortality, from 6 months to 4 years post-discharge | Clinical: 6 Laboratory: 2 Electrocardiographic: 1 |
0.75/NR | 33 |
| Dynamic TIMI risk score | STEMI | Pre-discharge | 1-year mortality | Nine admission variables of TIMI risk score plus parameters during the index hospitalisation: Clinical: 5 Electrocardiographic: 1 |
0.76/0.81 | 34,35,36 |
| RISK-PCI score | STEMI | Post-primary PCI | 30-day MACE and 30-day mortality | Clinical: 2 Laboratory: 3 Electrocardiographic: 3 Echocardiographic: 1 Angiographic: 3 |
0.83 (MACE-internal validation), 0.87 (mortality-internal validation)/NR | 37,38 |
| EPICOR prognostic model | ACS | Pre-discharge | 1-year mortality | Clinical: 8 Laboratory: 3 Echocardiographic: 1 |
0.81/0.78 | 39 |
| APEX-AMI risk score | STEMI | Post-primary PCI | 90-day mortality | Clinical: 4 Electrocardiographic: 2 Laboratory: 1 |
0.81/NR | 40 |
| Residual SYNTAX score (rSS) | ACS | After PCI | 1-year all-cause mortality | Same as baseline SYNTAX score | 0.63/NR | 41 |
| DAPT score | All PCI patients on DAPT | 12 months after DAPT | Ischaemia and bleeding between 12 and 30 months after PCI | Clinical: 5 Procedural: 3 plus CHF/LVEF<30% |
0.70 (ischaemia), 0.68 (bleeding)/0.64 (for both ischaemia and bleeding) | 48 |
| GUSTO score | STEMI | 30 days (event-free) after STEMI | 1-year mortality | Clinical: 4 ±1 angiographic and heart rate |
0.75 and 0.79 (with and without angiographic data)/NR | 49 |
Abbreviations: STEMI, ST-elevation myocardial infarction; NSTEMI, non-ST-elevation myocardial infarction; ACS, acute coronary syndrome; DAPT, dual antiplatelet therapy; MACE, major adverse cardiac event; PCI, percutaneous coronary intervention