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. 2018 Nov 12;4(11):e00898. doi: 10.1016/j.heliyon.2018.e00898

Table 5.

Acute effects of benzo[a]pyrene on GSH level (mean ± SD, n = 10).

Group Time Liver Lung Kidney Stomach Brain
Control 24 40.23 ± 5.64 49.32 ± 7.38 48.83 ± 6.71 47.93 ± 4.11 19.02 ± 4.73
12.5 mg/kg 24 58.96 ± 5.81c 62.12 ± 4.09c 68.07 ± 6.88c 68.84 ± 5.44c 35.71 ± 5.21c
25 mg/kg 24 56.42 ± 5.39c 60.73 ± 5.45c 64.26 ± 8.79c 66.44 ± 4.99c 32.60 ± 6.01c
50 mg/kg 24 52.94 ± 4.60c 57.78 ± 4.16b 60.25 ± 4.77c 63.39 ± 3.77c 27.76 ± 5.11c
100 mg/kg 24 50.47 ± 5.12c 53.52 ± 5.21 57.25 ± 6.23a 61.42 ± 3.13c 25.63 ± 4.11b
Control 48 39.62 ± 5.45 48.55 ± 7.42 47.25 ± 6.52 46.63 ± 4.52 18.23 ± 4.68
12.5 mg/kg 48 56.29 ± 6.95c 57.70 ± 5.80b 63.26 ± 7.09c 63.99 ± 4.56c 32.43 ± 5.57c
25 mg/kg 48 53.43 ± 5.85c 56.89 ± 5.58a 62.80 ± 6.41c 62.94 ± 4.95c 30.23 ± 6.62c
50 mg/kg 48 50.37 ± 5.57c 53.18 ± 4.16 58.21 ± 4.33c 60.28 ± 3.32c 25.08 ± 4.64b
100 mg/kg 48 47.75 ± 5.24b 51.42 ± 4.85 53.21 ± 5.11a 58.24 ± 4.45c 23.86 ± 4.42a
Control 72 39.12 ± 5.66 47.67 ± 7.51 46.68 ± 6.34 45.14 ± 4.33 18.14 ± 4.58
12.5 mg/kg 72 52.45 ± 6.96c 52.47 ± 4.35 60.73 ± 9.94b 58.69 ± 5.05c 30.83 ± 5.78c
25 mg/kg 72 51.14 ± 6.06c 52.12 ± 6.57 57.31 ± 8.48b 58.53 ± 3.03c 26.54 ± 5.72b
50 mg/kg 72 47.25 ± 6.02b 51.36 ± 4.62 54.03 ± 6.67a 57.22 ± 3.72c 22.13 ± 4.14
100 mg/kg 72 45.56 ± 5.31a 50.63 ± 5.14 50.03 ± 5.74 57.14 ± 4.31c 21.81 ± 4.06
a

P < 0.05.

b

P < 0.01.

c

P < 0.001 between the corresponding control and B[a]P treatment groups, respectively.