Table 6.

Acute effects of benzo[a]pyrene on GSSG level of various organs (mean ± SD, n = 10).

Group	Time	Liver	Lung	Kidney	Stomach	Brain
Control	24	6.22 ± 0.41	7.63 ± 0.55	7.56 ± 0.63	7.42 ± 0.65	2.94 ± 0.32
12.5 mg/kg	24	7.65 ± 0.55c	8.43 ± 0.74a	8.24 ± 0.74a	9.34 ± 0.78c	3.87 ± 0.36c
25 mg/kg	24	7.91 ± 0.63c	8.55 ± 0.75b	8.86 ± 0.82c	9.35 ± 0.72c	3.92 ± 0.38c
50 mg/kg	24	8.51 ± 0.71c	8.62 ± 0.71b	9.37 ± 0.92c	9.56 ± 0.85c	4.61 ± 0.41c
100 mg/kg	24	8.72 ± 0.73c	8.66 ± 0.78b	9.9 ± 0.96c	9.58 ± 0.86c	5.27 ± 0.51c
Control	48	6.13 ± 0.62	7.51 ± 0.68	7.31 ± 0.65	7.22 ± 0.71	2.82 ± 0.32
12.5 mg/kg	48	7.79 ± 0.75c	8.36 ± 0.82a	8.63 ± 0.82c	9.41 ± 0.86c	4.09 ± 0.36c
25 mg/kg	48	8.29 ± 0.81c	8.66 ± 0.85b	9.41 ± 0.78c	9.73 ± 0.87c	4.28 ± 0.35c
50 mg/kg	48	8.77 ± 0.85c	9.2 ± 0.84c	10.12 ± 0.96c	10.14 ± 0.92c	5.28 ± 0.45c
100 mg/kg	48	9.21 ± 0.88c	9.43 ± 0.88c	10.19 ± 0.92c	10.31 ± 0.96c	5.42 ± 0.52c
Control	72	6.05 ± 0.68	7.38 ± 0.71	7.22 ± 0.77	6.98 ± 0.65	2.65 ± 0.23
12.5 mg/kg	72	8.21 ± 0.83c	8.58 ± 0.85b	8.96 ± 0.84c	9.8 ± 0.82c	4.26 ± 0.41c
25 mg/kg	72	8.59 ± 0.83c	9.24 ± 0.92c	9.63 ± 0.86c	10.11 ± 0.92c	4.59 ± 0.45c
50 mg/kg	72	9.03 ± 0.86c	9.7 ± 0.95c	10.25 ± 0.86c	10.58 ± 0.93c	5.34 ± 0.53c
100 mg/kg	72	9.53 ± 0.92c	9.91 ± 0.86c	10.83 ± 0.96c	10.95 ± 0.96c	5.83 ± 0.55c

^aP < 0.05.

^bP < 0.01.

^cP < 0.001 between the corresponding control and B[a]P treatment groups, respectively.