Table 7.

Acute effects of benzo[a]pyrene on GSH/GSSG ratio of various organs (mean ± SD, n = 10).

Group	Time	Liver	Lung	Kidney	Stomach	Brain
Control	24	6.47 ± 0.32	6.46 ± 0.36	6.46 ± 0.41	6.45 ± 0.35	6.47 ± 0.36
12.5 mg/kg	24	7.71 ± 0.36c	7.36 ± 0.41a	8.26 ± 0.45c	7.37 ± 0.45c	9.23 ± 0.56c
25 mg/kg	24	7.13 ± 0.42b	7.1 ± 0.45b	7.25 ± 0.38c	7.1 ± 0.52b	8.31 ± 0.71c
50 mg/kg	24	6.22 ± 0.45	6.7 ± 0.52	6.43 ± 0.36	6.63 ± 0.51	6.02 ± 0.62
100 mg/kg	24	5.78 ± 0.52b	6.18 ± 0.55	5.78 ± 0.42b	6.41 ± 0.48	4.86 ± 0.52c
Control	48	6.46 ± 0.55	6.46 ± 0.56	6.46 ± 0.45	6.45 ± 0.53	6.46 ± 0.39
12.5 mg/kg	48	7.22 ± 0.56c	6.9 ± 0.61	7.33 ± 0.46c	6.8 ± 0.55	7.92 ± 0.63c
25 mg/kg	48	6.44 ± 0.71	6.56 ± 0.55	6.67 ± 0.45	6.46 ± 0.46	7.06 ± 0.66a
50 mg/kg	48	5.74 ± 0.51b	5.78 ± 0.46b	5.75 ± 0.51b	5.94 ± 0.38a	4.75 ± 0.42c
100 mg/kg	48	5.18 ± 0.45c	5.45 ± 0.46c	5.22 ± 0.52c	5.64 ± 0.42b	4.4 ± 0.41c
Control	72	6.46 ± 0.52	6.45 ± 0.48	6.46 ± 0.61	6.46 ± 0.45	6.46 ± 0.51
12.5 mg/kg	72	6.38 ± 0.51	6.11 ± 0.52	6.78 ± 0.58	5.99 ± 0.55a	7.23 ± 0.63b
25 mg/kg	72	5.95 ± 0.53a	5.64 ± 0.62b	5.95 ± 0.55	5.78 ± 0.46b	5.78 ± 0.55a
50 mg/kg	72	5.17 ± 0.55c	5.29 ± 0.58c	5.27 ± 0.48c	5.4 ± 0.49c	4.14 ± 0.43c
100 mg/kg	72	4.78 ± 0.46c	5.1 ± 0.47c	4.62 ± 0.41c	5.21 ± 0.42c	3.74 ± 0.32c

^aP < 0.05.

^bP < 0.01.

^cP < 0.001 between the corresponding control and B[a]P treatment groups, respectively.