Table 8.

Acute effects of benzo[a]pyrene on MDA level (mean ± SD, n = 10).

Group	Time	Liver	Lung	Kidney	Stomach	Brain
Control	24	6.05 ± 1.55	5.58 ± 1.26	3.98 ± 0.17	1.43 ± 0.15	1.49 ± 0.08
12.5 mg/kg	24	7.59 ± 1.19	7.09 ± 1.23	4.77 ± 0.67c	1.62 ± 0.12	1.63 ± 0.25c
25 mg/kg	24	7.95 ± 1.40	7.41 ± 1.73a	5.17 ± 1.08c	1.77 ± 0.19c	1.75 ± 0.19c
50 mg/kg	24	8.85 ± 2.11a	8.84 ± 1.82c	5.81 ± 1.24c	2.09 ± 0.12c	1.85 ± 0.29c
100 mg/kg	24	9.57 ± 2.38a	9.23 ± 1.32c	6.22 ± 1.26c	2.15 ± 0.16c	2.05 ± 0.21c
Control	48	6.12 ± 1.46	5.66 ± 1.21	4.00 ± 0.18	1.45 ± 0.15	1.51 ± 0.09
12.5 mg/kg	48	7.96 ± 1.76	7.36 ± 1.41b	4.86 ± 0.31c	1.76 ± 0.16c	1.73 ± 0.23c
25 mg/kg	48	8.16 ± 1.06	7.80 ± 1.16c	5.55 ± 0.82c	1.84 ± 0.18c	1.96 ± 0.25c
50 mg/kg	48	9.58 ± 2.14b	8.92 ± 2.16c	5.93 ± 1.13c	1.99 ± 0.15c	1.99 ± 0.22c
100 mg/kg	48	11.63 ± 2.47c	9.35 ± 2.72c	6.33 ± 1.06c	2.18 ± 0.18c	2.39 ± 0.26c
Control	72	6.35 ± 1.35	5.72 ± 1.24	4.02 ± 0.18	1.86 ± 0.13	1.52 ± 0.11
12.5 mg/kg	72	8.61 ± 1.84	7.49 ± 1.49c	4.94 ± 0.84c	1.95 ± 0.12c	1.76 ± 0.24c
25 mg/kg	72	9.22 ± 1.46b	8.54 ± 2.62c	6.91 ± 0.96c	2.06 ± 0.13c	2.14 ± 0.32c
50 mg/kg	72	11.93 ± 2.19c	11.54 ± 2.62c	7.21 ± 1.38c	2.14 ± 0.19c	2.21 ± 0.27c
100 mg/kg	72	14.03 ± 2.35c	13.12 ± 3.16c	7.96 ± 1.45c	2.36 ± 0.21c	2.58 ± 0.31c

^aP < 0.05.

^bP < 0.01.

^cP < 0.001 between the corresponding control and B[a]P treatment groups, respectively.