Table 2.

Body and Heart Weights and Echocardiographic Data

	Control	SS	VNS	p Value
Body and heart weights
n	5	6	6
Body weight, g	299 ± 8	278 ± 6∗	274 ± 5	0.049
RV weight, mg	136 ± 4	353 ± 16†	241 ± 15‡	<0.001
LV+S weight, mg	546 ± 9	584 ± 19	515 ± 17§	0.023
RVH	0.25 ± 0.01	0.61 ± 0.02†	0.47 ± 0.02‡	<0.001
Echocardiography
n	4	5	5
RVDd, mm	1.9 ± 0.1	3.4 ± 0.3†	2.5 ± 0.1§	<0.001
RVDs, mm	1.2 ± 0.1	2.7 ± 0.3†	1.7 ± 0.1§	<0.001
RVWT, mm	0.83 ± 0.03	1.28 ± 0.04†	1.05 ± 0.05§	<0.001
PAAT/CL, %	20.8 ± 1.8	8.8 ± 0.6†	14.6 ± 1.9‡	<0.001
Heart rate, beats/min	354 ± 7	311 ± 14	329 ± 14	0.099

Values are mean ± SEM. Differences were tested by using one-way analysis of variance, followed by post hoc Tukey-Kramer test.

LV + S = left ventricle plus septum; RV = right ventricular; RVH = ratio of right ventricle/LV + S; RVDd = RV diastolic dimensions; RVDs = RV systolic dimensions; PAAT/CL = pulmonary artery acceleration time normalized to cycle length; RVWT = RV wall thickness; other abbreviations as in Table 1.

^∗p < 0.05 and †p < 0.01 vs. control.

^§p < 0.05 and ‡p < 0.01 vs. SS.