Table 3.
Whole brain effects of the emotion regulation task.
| k |
Side |
MNI |
t-value |
|||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| HC + MDD | ||||||
| Internal>View | ||||||
| Precuneus | 153 | L | −6 | −54 | 34 | 4.06 |
| 2. Maximum: PCC | L | −4 | −48 | 18 | 4.04 | |
| Angular Gyrus | 124 | L | −48 | −64 | 28 | 4.27 |
| View>Internal | No suprathreshold activation | |||||
| External>View | ||||||
| Precuneus | 100 | L | −6 | −56 | 32 | 3.77 |
| View>External | No suprathreshold activation | |||||
| Internal Happy>External Happy | No suprathreshold activation | |||||
| External Sad>Internal Sad | No suprathreshold activation | |||||
| HC > MDD | ||||||
| View | No suprathreshold activation | |||||
| Internal | ||||||
| Lingual Gyrus | 266 | R | 8 | −76 | 2 | 4.77 |
| Lingual Gyrus | 118 | L | −8 | −76 | −6 | 4.47 |
| External | No suprathreshold activation | |||||
| Internal vs. View | No suprathreshold activation | |||||
| External vs. View | No suprathreshold activation | |||||
| Internal Positive>External Positive | ||||||
| Lingual Gyrus | 152 | L | −12 | −52 | −4 | 4.19 |
| External Negative>Internal Negative | No suprathreshold activation | |||||
| MDD > HC | ||||||
| View | ||||||
| Fusiform Gyrus | 106 | L | −18 | −88 | −8 | 5.95 |
| Internal | ||||||
| Fusiform Gyrus | 99 | L | −18 | −88 | −8 | 5.26 |
| External | ||||||
| Lingual Gyrus | 145 | L | −18 | −86 | −8 | 5.89 |
| Fusiform Gyrus | 120 | L | −40 | −64 | −18 | 4.17 |
| Fusiform Gyrus | 100 | R | 30 | −80 | −10 | 5.71 |
| Fusiform Gyrus | 95 | R | 32 | −48 | −18 | 4.79 |
| Internal vs. View | No suprathreshold activation | |||||
| External vs. View | No suprathreshold activation | |||||
| Internal Positive>External Positive | No suprathreshold activation | |||||
| External Negative>Internal Negative | No suprathreshold activation | |||||
| HC | ||||||
| Internal>View | ||||||
| Middle Temporal Gyrus | 135 | L | −52 | −14 | −12 | |
| Lingual Gyrus | 91 | L | −10 | −54 | 0 | 3.88 |
| View>Internal | No suprathreshold activation | |||||
| External vs. View | No suprathreshold activation | |||||
| Internal Positive>External Positive | ||||||
| Parahippocampal Gyrus | 190 | L | −18 | −40 | −4 | 4.58 |
| External Negative>Internal Negative | No suprathreshold activation | |||||
| MDD | ||||||
| Internal vs. View | No suprathreshold activation | |||||
| External>View | ||||||
| Precuneus/PCC | 92 | L | −4 | −60 | 18 | 4.33 |
| View>External | No suprathreshold activation | |||||
| Internal Positive>External Positive | No suprathreshold activation | |||||
| External Negative>Internal Negative | ||||||
| Superior Frontal Gyrus | 209 | R | 20 | 22 | 42 | 4.77 |
Whole-brain effects across groups, between groups, and within groups for the emotion regulation task. Results are Monte-Carlo corrected and cluster size (k), side, MNI coordinates and t-values are given.
Note: HC = Healthy controls; MDD = Patients with major depressive disorder; L = Left; R = Right; PCC = Posterior Cingulate Cortex.