Table 3. Imaging findings of confirmed congenital brain abnormalities cases, according to the timing of maternal exanthema, Salvador, Brazil, April 2015–July 2016 (n = 151).
Congenital brain abnormalities | Pregnancy trimester of exanthema | |||||||
---|---|---|---|---|---|---|---|---|
First (n = 75) |
Second (n = 24) |
Third (n = 9) |
Without exanthema (n = 43) |
|||||
n | % | n | % | n | % | n | % | |
Intracranial calcifications | 68 | 90.7 | 23 | 95.8 | 7 | 77.8 | 32 | 74.4 |
Ventriculomegaly | 48 | 64.0 | 18 | 75 | 8 | 88.9 | 28 | 65.1 |
Agenesis of the corpus callosum | 11 | 14.7 | 3 | 12.5 | 2 | 22.2 | 4 | 9.3 |
Dysgenesis of the corpus callosum | 8 | 10.7 | 5 | 20.8 | 0 | 0.0 | 5 | 11.6 |
Lissencephaly | 6 | 8.0 | 4 | 16.7 | 2 | 22.2 | 4 | 9.3 |
Cerebellar abnormalitiesa | 6 | 8.0 | 1 | 4.2 | 0 | 0.0 | 1 | 2.3 |
Arthrogryposis | 6 | 8.0 | 2 | 8.3 | 0 | 0.0 | 2 | 4.7 |
Oligohydramnios | 12 | 16.0 | 1 | 4.2 | 0 | 0.0 | 3 | 7.0 |
Intrauterine growth restriction | 9 | 12.0 | 3 | 12.5 | 0 | 0.0 | 1 | 2.3 |
Subependymal cysts | 7 | 9.3 | 1 | 4.2 | 1 | 11.1 | 6 | 14.0 |
a Cerebellar vermis agenesis or cerebellar hypoplasia.