Table 2.
Comparison of pulmonary function test, arterial blood gas, exercise capacity, dyspnea, QOL, anxiety and depression scores of patients.a
| Variables | All patients (n = 359) | Group 1 (n = 212) | Group 2 (n = 147) | p valueb |
|---|---|---|---|---|
| PFT | ||||
| FEV1 (%) | 39 (29, 52) | 40 (30, 59) | 37 (28, 48) | 0.024** |
| FEV1/FVC | 56 (48, 66) | 56 (48, 67) | 57 (47, 64) | 0.363 |
| TLCO (%) | 33 (20, 45) | 34 (21, 47) | 32 (17, 42) | 0.181 |
| ABGA | ||||
| PaO2 (mmHg) | 72 (63, 80) | 72 (63, 80) | 71 (63, 80) | 0.859 |
| PaCO2 (mmHg) | 40 (38, 45) | 40 (37, 45) | 41 (38, 46) | 0.578 |
| SaO2 (mmHg) | 95 (93, 96) | 95 (93,96) | 95 (92, 96) | 0.960 |
| 6-MWD (m) | 340 (258, 401) | 350 (290, 410) | 310 (220, 390) | 0.001** |
| mMRC dyspnea score | 3 (2, 3) | 2 (2, 3) | 3 (2, 4) | <0.001** |
| SGRQ | ||||
| Symptom | 59 (44, 73) | 58 (42, 74) | 61 (45, 72) | 0.986 |
| Activity | 67 (54, 86) | 66 (54, 86) | 80 (59, 87) | 0.015** |
| Impact | 49 (33, 67) | 46 (31, 65) | 54 (43, 73) | 0.010** |
| Total | 57 (42, 72) | 55 (41, 71) | 63 (49, 72) | 0.014** |
| HAD | ||||
| Anxiety | 8 (5, 11) | 8 (4, 11) | 8 (5, 12) | 0.203 |
| Depression | 7 (4, 10) | 7 (4, 10) | 7 (5, 11) | 0.318 |
QOL: quality of life; PFT: pulmonary function test, FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; TLCO: carbon monoxide diffusing capacity; ABGA: arterial blood gas analysis; PaO2: partial arterial oxygen pressure; PaCO2: partial arterial oxygen pressure; SaO2: arterial oxygen saturation; 6-MWD: 6-minute walk distance; mMRC: Modified Medical Research Council; SGRQ: St George Respiratory Questionnaire, HAD: Hospital Anxiety and Depression.
aData are expressed as median (interquartile range) and Δ values show changes between pre- and posttest.
bMann–Whitney U test.
**p < 0.05.