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. 2018 Nov 13;22:293. doi: 10.1186/s13054-018-2234-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Incremental cost-effectiveness plane for procalcitonin (PCT) guidance compared with standard of care for costs until one year after ICU admission. This incremental cost-effectiveness plane shows the impact of the use of a PCT-guided antibiotic treatment algorithm, as compared to standard of care, on the difference in quality-adjusted life years (QALYs) (until one year after ICU admission) and accompanying healthcare-related costs within this one-year time period. In addition, the willingness-to-pay (WTP) thresholds of €20,000/QALY and €80,000/QALY are shown. The result is based on 10,000 bootstrap samples