Table 3.
Preoperative serum levels of CXCL8 (pg/ml) in relation to other variables for men who underwent radical prostatectomy and had available information on serum CXCL8 (n = 95)
Total population (n = 95) | |||||
Median serum CXCL8, pg/ml (min-max) | 9.97 (3.36–155.53) | ||||
By C. acnes category | C. acnes + (n = 58) | C. acnes- (n = 37) | |||
Median serum CXCL8, pg/ml (min-max) | 10.01 (5.05–130.93) | 9.68 (3.36–155.53) | p = 0.658a | ||
Gleason sum | Gleason 6 (n = 36) | Gleason 3 + 4 (n = 41) | Gleason 4 + 3 (n = 15) | Gleason 8+ (n = 3) | |
Median serum CXCL8, pg/ml (min-max) | 10.05 (4–155.53) | 9.21 (3.36–83.2) | 9.96 (5.95–16.07) | 11.16 (9.41–12.14) | p = 0.843a |
Positive sugical margins | No (n = 62) | Yes (n = 33) | |||
Median serum CXCL8, pg/ml (min-max) | 10.01 (3.36–155.53) | 9.41 (4.79–38.16) | p = 0.344a | ||
pT stage | pT2 (n = 86) | pT3 (n = 9) | |||
Median serum CXCL8, pg/ml (min-max) | 9.99 (3.36–155.53) | 9.41 (6.24–20.53) | p = 0.576a | ||
PSA | |||||
By PSA quartile | < 4.6 ng/ml | ≥4.6, < 6.4 ng/ml | ≥6.4, < 9.0 ng/ml | ≥9 ng/ml | |
Median serum CXCL8, pg/ml (min-max) | 9,68 (5,05-130,93) | 10,03 (4,79-155,53) | 8,93 (4–38,16) | 10,65 (3,36-83,2) | p = 0.646a |
Non-parametric correlation | |||||
Correlation coefficient | 0.069 | p = 0.505b | |||
Age | |||||
By age quartile | < 61.3 years | ≥61.3, < 64.7 years | ≥64.7, < 67.1 years | ≥67.1 years | |
Median serum CXCL8, pg/ml (min-max) | 10,09 (3,36-155,53) | 10,09 (3,36-155,53) | 9,21 (5,26-83,2) | 11,16 (5,4-62,26) | |
Non-parametric correlation | |||||
Correlation coefficient | 0.044 | p = 0.674b | |||
Prostate volume | |||||
By volume quartile | 0–26 ml | 27–33 ml | 34–50 ml | 51–138 ml | |
Median serum CXCL8, pg/ml (min-max) | 10.28 (6.24–16.68) | 8.89 (3.36–83.2) | 10.8 (4–130.93) | 9.68 (5.26–155.53) | p = 0.468a |
Non-parametric correlation | |||||
Correlation coefficient | 0.045 | p = 0.681b |
ap-value fron Kruskal-Wallis Test/Mann-Whitney U Test; bp-value from Spearman correllation