Table 3.
Univariate analysis on risk factors for in-hospital death
| Parameter | Discharge alive (n = 781) | In-hospital death (n = 379) | *P-value | OR (CI 95) |
|---|---|---|---|---|
| Vancomycin resistance | 6.7% (52) | 13.7% (52) | < 0.001 | 2.273 (1.512-3.417) |
| E. faecium | 44.7% (349) | 65.2% (247) | < 0.001 | 2.311 (1.792-2.979) |
| E. faecalis | 55.3% (432) | 34.8% (132) | 1 = Reference | |
| Male | 61.2% (478) | 62.0% (235) | 0.792 | 1.037 (0.805-1.334) |
| Age (years), median (IQR) | 64.0 (51–73) | 66.0 (56–74) | 0.011 | n.a. |
| Heart disease | 25.1% (196) | 35.4% (134) | < 0.001 | 1.641 (1.258-2.14) |
| Vascular disease | 19.6% (153) | 27.7% (105) | 0.002 | 1,57 (1,18-2.091) |
| Lung disease | 19.6% (153) | 26.1% (99) | 0.011 | 1.461 (1.093-1.952) |
| Rheumatic disease | 2.6% (20) | 4.7% (18) | 0.050 | 1.895 (0,99-3.626) |
| Gastrointestinal disease | 4.1% (32) | 5.8% (22) | 0.195 | 1,44 (0,825-2.515) |
| Diabetes | 26.8% (209) | 27.4% (104) | 0.807 | 1.033 (0,784-1.361) |
| Renal disease | 46.9% (366) | 78.1% (296) | < 0.001 | 4.055 (3.061-5.371) |
| Liver disease | 18.2% (142) | 42.2% (160) | < 0.001 | 3.283 (2.498-4.314) |
| Cancer/Immunological disease | 41.4% (323) | 45.4% (172) | 0.194 | 1.176 (0,918-1.506) |
| Neurological disease | 10.8% (84) | 9.0% (34) | 0.346 | 0,817 (0.537-1.241) |
Categorical variables displayed as percentage and number; continuous variable displayed as median and interquartile range. *P-value, categorical variables tested with Chi-square test, continuous variable tested with Wilcoxon rank sum test. BSI = blood stream infection, IQR = interquartile range, OR = odds ratio, CI95 = 95% confidence interval. VRE = vancomycin-resistant enterococcus, VSE = vancomycin-susceptible enterococcus. N.a. = not applicable
Bold entries represent statistically significant factors