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. 2018 Oct 31;22(Suppl 3):S139–146. doi: 10.5213/inj.1836228.114

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Copyright © 2018 Korean Continence Society

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4. — Effect of dexmedetomidine on D1 dopamine receptor (D1DR) in the pre-frontal cortex (PFC), striatum, and substantia nigra (SN). Upper panel: The results of band detection using the enhanced chemiluminescence detection kit in PFC (left), striatum (middle), and SN (right). Lower panel: The relative expression of D1 dopamine receptor in each group. A, control group; B, sleep deprivation group; C, sleep deprivation and 0.5 μg/kg dexmedetomidine-treated group; D, sleep deprivation and 1 μg/kg dexmedetomidinetreated group; E, sleep deprivation and 2 μg/kg dexmedetomidine-treated group. *P<0.05 compared to the control group. # P<0.05 compared to the sleep deprivation group.