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An suppressed the expressions of TGF-β1 and ALK5 and the ratio of p-smad/smad. (A) The protein levels of TGF-β1, ALK5, p-smad, and smad as shown by Western blot analysis. The protein levels of (B) TGF-β1 and (C) ALK5 were decreased by An and (D) the ratio of p-smad/smad was also reduced by An. * P<0.05 compared with control group.
