Table 4.
Results of the transcription factor binding site prediction according to the software FIMO for the tested SNPs
| SNP | Allele | Transcription factor | Modification (in the presence of the minor allele) | Strand | p-value | q-value | Matched sequence |
|---|---|---|---|---|---|---|---|
| rs749759 | G | NR0B1 | Removed | “-” | 1.96e-05 | 0.022 | CCTCCCACTC |
| rs749759 | G | Sp4 | Removed | “+” | 2.54e-05 | 0.0266 | GGGGCCAGGGGAGTGgGAGGCACG |
| rs749759 | G | ZBTB7B | Removed | “+” | 6.36e-05 | 0.0226 | GGGGCCAGGGGAGTGgGAGGCA |
| rs749759 | G | EGR-2 | Removed | “+” | 8.97e-05 | 0.033 | GGAGTGgGAGG |
| rs749759 | G | Sp3 | Removed | “-” | 7.23e-05 | 0.0255 | CCCACTCCCCT |
| rs72735260 | T | AR | Added | “+” | 2.41e-05 | 0.0273 | AGGGAAAGAGTGtACCC |
| rs72735260 | T | RARα::RXRα | Added | “-” | 3.85e-05 | 0.0423 | GGGTCAGGGGCCGGGTA |
| rs10881578 | – | – | – | – | – | – | – |
| rs10776909 | C | NR3C1 | Removed | “+” | 1.16e-05 | 0.013 | GGGAcTTTGAGTTC |
| rs10776909 | C | AR | Removed | “-” | 2.96e-05 | 0.0333 | GGGAACTCAAAGTCC |
| rs10776909 | C | IRF-5 | Removed | “-” | 4.59e-05 | 0.0246 | GAGAGGGGAACTCAAAGTCC |
| rs10776909 | T | MZF-1 | Added | “+” | 6.33e-05 | 0.023 | TGTGGGGAt |
| rs10776909 | T | NR2E3 | Added | “-” | 3.34e-05 | 0.0364 | GAACTCAAAATCCC |
| rs10776909 | C | NR3C2 | Removed | “-” | 1.72e-05 | 0.0161 | GGGAACTCAAAGTCCCC |
| rs10776909 | C | HNF-4-α | Removed | “+” | 4.13e-05 | 0.0455 | GGGGAcTTTGAGTTC |
| rs10776909 | C | HNF-4-ɣ | Removed | “-” | 4.6e-05 | 0.0498 | GGAACTCAAAGTCCC |
| rs2281997 | – | – | – | “-” | – | – | – |
| rs2279238 | A | Klf8 | Added | “+” | 2.29e-05 | 0.0263 | CAGtGTGTG |
| rs2279238 | A | ZBTB3 (Mus musculus) | Added | “+” | 8.54e-06 | 0.00974 | TATGCAGtG |
| rs7120118 | C | IRF-4 | Added | “-” | 7.59e-06 | 0.00841 | ACTCATGAAATGAGAAAT |
| rs11039155 | G | ETV7 | Removed | “+” | 4.19e-05 | 0.0459 | GCTCCAGgAAGAGATGT |
| rs11039155 | G | Elf-1 | Removed | “+” | 4.34e-05 | 0.0484 | GCTCCAGgAAGAG |
| rs11039155 | G | Stat3 | Removed | “+” | 2.64e-05 | 0.0293 | CTCCAGgAAG |
The table contains only statistically significant in silico-predicted differentially bound transcription factors