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. 2018 May 8;39(43):3879–3892. doi: 10.1093/eurheartj/ehy249

Figure 8.

Figure 8

Proposed hypertrophic cardiomyopathy mechanisms. Phenotypes investigated (red) in the developed model of hypertrophic cardiomyopathy of R453C-β-myosin heavy chain human pluripotent stem cell-cardiomyocytes; putative rescue drugs (purple). LTCC, L-type calcium channels; NAC, N-acetyl-cysteine; NCX, sodium-calcium exchange pump.