Figure 3.

Glial Cells Are Not a Cell Origin for iDALs

(A) iDALs do not come from resident NG2 glia. NG2 glia and their derivatives were traced in Pdgfra-CreER^T;Rosa-tdT mice after Tam injections. Representative confocal images show that TH⁺ iDALs are not traced by the reporter tdT (n = 0 tdT⁺TH⁺ cells from three mice). Scale bar, 50 μm.

(B) iDALs do not come from resident astrocytes. Astrocytes and their derivatives were traced in mGfap-Cre;Rosa-tdT mice. Representative confocal images show TH⁺ iDALs are not traced by the reporter tdT (n = 0 tdT⁺TH⁺ cells from three mice). Scale bar, 50 μm.

See also Figures S3 and S4.