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. 2018 Oct 11;11(5):1156–1170. doi: 10.1016/j.stemcr.2018.09.004

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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iDALs Express Markers for DA Neurons

(A) TH⁺ iDALs in the striatum express markers for DA neurons but not the other neuronal subtypes. Single-plane confocal images at 1 μm thickness are shown. Scale bar, 20 μm.

(B) A genetic approach to trace dopamine transporter-expressing cells. tdT⁺ somas were not observed in the core striatum, although numerous neuronal processes were clearly labeled in this region. Scale bar, 100 μm.

(C) Somas of iDALs but not endogenous striatal neurons are genetically labeled in Dat-Cre;Rosa-tdT reporter mice. Empty virus-injected brains were used as controls. Scale bar, 50 μm.